ID Q47SE5_THEFY Unreviewed; 606 AA.
AC Q47SE5;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 119.
DE RecName: Full=maltose alpha-D-glucosyltransferase {ECO:0000256|ARBA:ARBA00012619};
DE EC=5.4.99.16 {ECO:0000256|ARBA:ARBA00012619};
DE AltName: Full=Maltose alpha-D-glucosyltransferase {ECO:0000256|ARBA:ARBA00031378};
GN OrderedLocusNames=Tfu_0584 {ECO:0000313|EMBL:AAZ54622.1};
OS Thermobifida fusca (strain YX).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Thermobifida.
OX NCBI_TaxID=269800 {ECO:0000313|EMBL:AAZ54622.1};
RN [1] {ECO:0000313|EMBL:AAZ54622.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=YX {ECO:0000313|EMBL:AAZ54622.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA Larimer F., Land M., Lykidis A., Richardson P.;
RT "Complete sequence of Thermobifida fusca YX.";
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-maltose = alpha,alpha-trehalose; Xref=Rhea:RHEA:15145,
CC ChEBI:CHEBI:16551, ChEBI:CHEBI:17306; EC=5.4.99.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001595};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family. TreS
CC subfamily. {ECO:0000256|ARBA:ARBA00005496}.
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DR EMBL; CP000088; AAZ54622.1; -; Genomic_DNA.
DR AlphaFoldDB; Q47SE5; -.
DR STRING; 269800.Tfu_0584; -.
DR CAZy; GH13; Glycoside Hydrolase Family 13.
DR KEGG; tfu:Tfu_0584; -.
DR eggNOG; COG0366; Bacteria.
DR HOGENOM; CLU_006462_2_1_11; -.
DR OrthoDB; 3203135at2; -.
DR BRENDA; 5.4.99.16; 6298.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0047471; F:maltose alpha-D-glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd11334; AmyAc_TreS; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR032091; Malt_amylase_C.
DR InterPro; IPR045857; O16G_dom_2.
DR InterPro; IPR012810; TreS/a-amylase_N.
DR NCBIfam; TIGR02456; treS_nterm; 1.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF219; MALTOSE ALPHA-D-GLUCOSYLTRANSFERASE; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF16657; Malt_amylase_C; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Hydrolase {ECO:0000313|EMBL:AAZ54622.1};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:AAZ54622.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 39..441
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..598
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 606 AA; 70201 MW; B4E258656FAC7C88 CRC64;
MTTQPAPGAR PTPTGSVPDT FTHAKPRDPY WYKHAVFYEV LVRGFYDSNG DGTGDLRGLI
EKLDYLQWLG IDCLWLLPIY ESPLRDGGYD VSDYMKILPE FGRISDFVEL VEKAHQRGIR
VITDLVMNHT SDQHPWFQAS RHDPDGPYGN FYVWSDTTER YSDARIIFID TEQSNWTYDE
VRGQYYWHRF FSHQPDLNFE NPDVQDAILE VMRFWLDLGI DGFRLDAVPY LYEREGTNCE
NLKETHEFLK RIRAEVDRLY PDRVLLSEAN QWPADVVDYF GDYESGGDEC HMNFHFPLMP
RMFMAVRREQ RYPISEILAQ TPPIPRNCQW AIFLRNHDEL TLEMVSDEER DYMYSEYAKD
PRMRANMGIR RRLAPLLEND LNQIKLFTAL LLSLPGSPVL YYGDEIGMGD NIWLGDRDSV
RTPMQWTPDR NAGFSRCDPG RLYLPVIMDP IYGYQAINVE AQQNNPNSLL NWTRNMIQIR
KQHPVFGTGD FTELHASNPS VFAFVREYGD DRMLCVNNLS RFPQPVELDL RRFEGITPIE
CTGGVHFPPI GELPYLLTLP GHGFYWFQLP PVAEEQPLAQ PVTTVPAAPQ PPAPADRPAS
DPTQRS
//
