ID Q48TY1_STRPM Unreviewed; 262 AA.
AC Q48TY1;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 2.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=GTP cyclohydrolase 1 type 2 homolog {ECO:0000256|ARBA:ARBA00022112};
GN OrderedLocusNames=M28_Spy0712 {ECO:0000313|EMBL:AAX71825.2};
OS Streptococcus pyogenes serotype M28 (strain MGAS6180).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=319701 {ECO:0000313|EMBL:AAX71825.2, ECO:0000313|Proteomes:UP000009292};
RN [1] {ECO:0000313|EMBL:AAX71825.2, ECO:0000313|Proteomes:UP000009292}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGAS6180 {ECO:0000313|EMBL:AAX71825.2,
RC ECO:0000313|Proteomes:UP000009292};
RX PubMed=16088825; DOI=10.1086/430618;
RA Green N.M., Zhang S., Porcella S.F., Nagiec M.J., Barbian K.D., Beres S.B.,
RA LeFebvre R.B., Musser J.M.;
RT "Genome sequence of a serotype M28 strain of group A Streptococcus:
RT potential new insights into puerperal sepsis and bacterial disease
RT specificity.";
RL J. Infect. Dis. 192:760-770(2005).
CC -!- SUBUNIT: Homohexamer. {ECO:0000256|ARBA:ARBA00011643}.
CC -!- SIMILARITY: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
CC {ECO:0000256|ARBA:ARBA00006964}.
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DR EMBL; CP000056; AAX71825.2; -; Genomic_DNA.
DR RefSeq; WP_021340967.1; NC_007296.2.
DR AlphaFoldDB; Q48TY1; -.
DR KEGG; spb:M28_Spy0712; -.
DR HOGENOM; CLU_037423_2_0_9; -.
DR Proteomes; UP000009292; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1390.30; NIF3 (NGG1p interacting factor 3)-like; 2.
DR InterPro; IPR002678; DUF34/NIF3.
DR InterPro; IPR036069; DUF34/NIF3_sf.
DR NCBIfam; TIGR00486; YbgI_SA1388; 1.
DR PANTHER; PTHR13799; NGG1 INTERACTING FACTOR 3; 1.
DR PANTHER; PTHR13799:SF13; NIF3-LIKE PROTEIN 1; 1.
DR Pfam; PF01784; DUF34_NIF3; 1.
DR SUPFAM; SSF102705; NIF3 (NGG1p interacting factor 3)-like; 1.
PE 3: Inferred from homology;
SQ SEQUENCE 262 AA; 29389 MW; 5EE4CD8A464D2F29 CRC64;
MKAKTLIDAY EAFCPLDLSM ERDVKGLQMG SLDKDIRKVM ITLDIRESTV AEAIKNEVDL
IITKHAPIFK PLKDLVSSPQ RDILLDLVKH DISVYVSHTN IDIVPGGLND WFCDLLEIKE
ATYLSETKEG FGIGRIGTVK EQALEELASK VKRVFDLDTV RLIRYDKENP LISKIAICGG
SGGEFYQDAV QKGADVYITG DIYYHTAQEM LTEGLFAVDP GHHIEVLFTE KLKEKLQGWK
EENGWDVSII SSKASTNPFS HL
//
