ID Q4D1D5_TRYCC Unreviewed; 200 AA.
AC Q4D1D5;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=tRNA ligase phosphodiesterase domain-containing protein {ECO:0000259|Pfam:PF08302};
GN ORFNames=Tc00.1047053509367.51 {ECO:0000313|EMBL:EAN86338.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN86338.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN86338.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN86338.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN86338.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAHK01001242; EAN86338.1; -; Genomic_DNA.
DR RefSeq; XP_808189.1; XM_803096.1.
DR AlphaFoldDB; Q4D1D5; -.
DR PaxDb; 353153-Q4D1D5; -.
DR EnsemblProtists; EAN86338; EAN86338; Tc00.1047053509367.51.
DR GeneID; 3538552; -.
DR KEGG; tcr:509367.51; -.
DR VEuPathDB; TriTrypDB:TcCLB.509367.51; -.
DR eggNOG; ENOG502R07Z; Eukaryota.
DR InParanoid; Q4D1D5; -.
DR OMA; IEIFCAR; -.
DR OrthoDB; 169417at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003972; F:RNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:InterPro.
DR InterPro; IPR015965; tRNA_lig_PDEase.
DR Pfam; PF08302; tRNA_lig_CPD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 110..173
FT /note="tRNA ligase phosphodiesterase"
FT /evidence="ECO:0000259|Pfam:PF08302"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAN86338.1"
SQ SEQUENCE 200 AA; 21526 MW; C1A4CBB553963FF8 CRC64;
APLIEVSVAD DTAAIARRVW VELSAIGLTD IPEIQTLDMA AALGVANTCE SFLCRFPRHV
EYAAIQIASP ERVLELVPPE MLDGKKVQKA FHVTTLYLGR DACKDPVLLQ QLVGLLGESI
ELTLTSVASD PKGTAIAVRN EGEFPCENVH PHITIANAPG VPPAHSNELL DDSHADDPCR
TVDSLPAGTR VTGTFVFRWP
//
