ID Q4DAI0_TRYCC Unreviewed; 401 AA.
AC Q4DAI0;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Aminoacylase, putative {ECO:0000313|EMBL:EAN89533.1};
DE EC=3.5.1.14 {ECO:0000313|EMBL:EAN89533.1};
GN ORFNames=Tc00.1047053506363.90 {ECO:0000313|EMBL:EAN89533.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN89533.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN89533.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN89533.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN89533.1}.
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DR EMBL; AAHK01000735; EAN89533.1; -; Genomic_DNA.
DR RefSeq; XP_811384.1; XM_806291.1.
DR AlphaFoldDB; Q4DAI0; -.
DR SMR; Q4DAI0; -.
DR PaxDb; 353153-Q4DAI0; -.
DR EnsemblProtists; EAN89533; EAN89533; Tc00.1047053506363.90.
DR GeneID; 3542353; -.
DR KEGG; tcr:506363.90; -.
DR eggNOG; ENOG502QQEM; Eukaryota.
DR InParanoid; Q4DAI0; -.
DR OMA; VNKGMMH; -.
DR OrthoDB; 3684955at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0004046; F:aminoacylase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.70.360; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR017439; Amidohydrolase.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR NCBIfam; TIGR01891; amidohydrolases; 1.
DR PANTHER; PTHR11014:SF63; METALLOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G09600)-RELATED; 1.
DR PANTHER; PTHR11014; PEPTIDASE M20 FAMILY MEMBER; 1.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR PIRSF; PIRSF005962; Pept_M20D_amidohydro; 1.
DR SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EAN89533.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 189..266
FT /note="Peptidase M20 dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07687"
SQ SEQUENCE 401 AA; 42793 MW; D870A28F91455ECB CRC64;
MSFINVLISA VQPEVVQWRR HIHENPYLAY EEQPTADYVA SVLTAMPAPL EIRRLTLNSV
IADLRGGAGE GPIYALRADM DALPLQEESG EPFSSKRPGV MHACGHDAHT AMLLGAVKVL
CQVKDKIRGT VRFIFQHAEE VIPSGAKQLV QLGVLEGVKM IFGLSVDVTK PLGTVFCKSG
VMMGACNDFD IVIKGAGGHA SQPELCTDPI VIAAEVVMGL QTIVSRRIGA LTAPVLSVTT
FHGGTGSYNV IPDTAHLRGT LRCLDRDVQA LVPGLMEEIV AGIAKAHGAQ HEISWLEPNI
VTYNDPAAYE IVRNVAQRVI DGVSFVDLST AMMGVADFAE YGSVVPGCLF WLGVGDSSKS
SISNHNYSSR YCMSETAMEG GVKMHVGLVA ALSMSDGTFA G
//
