ID Q4DE30_TRYCC Unreviewed; 325 AA.
AC Q4DE30;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE SubName: Full=RNA-binding protein, putative {ECO:0000313|EMBL:EAN90786.1};
GN ORFNames=Tc00.1047053506649.80 {ECO:0000313|EMBL:EAN90786.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN90786.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN90786.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN90786.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN90786.1}.
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DR EMBL; AAHK01000588; EAN90786.1; -; Genomic_DNA.
DR RefSeq; XP_812637.1; XM_807544.1.
DR AlphaFoldDB; Q4DE30; -.
DR SMR; Q4DE30; -.
DR STRING; 353153.Q4DE30; -.
DR PaxDb; 353153-Q4DE30; -.
DR EnsemblProtists; EAN90786; EAN90786; Tc00.1047053506649.80.
DR GeneID; 3543883; -.
DR KEGG; tcr:506649.80; -.
DR eggNOG; KOG1190; Eukaryota.
DR InParanoid; Q4DE30; -.
DR OMA; MIVYQIF; -.
DR OrthoDB; 4825346at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12421; RRM1_PTBP1_hnRNPL_like; 1.
DR CDD; cd12422; RRM2_PTBP1_hnRNPL_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR PANTHER; PTHR15592:SF18; SMOOTH, ISOFORM T; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 77..152
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 163..257
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 32..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..303
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 36369 MW; 67262B1F74FE220C CRC64;
MYGQQFPQNS LYGTPNMMSY HGVMQPPISP QGTAPGMLSN YNNNPNRGGY DASQANRNMG
QRQPPRQRNN EIGEVSRVIH MRNITPNVTQ LSIQNLVQNF GNIKHIVMLR QMNQALVEME
STKSAQQLVD FFRQTGYAEI DGRRVYIRYS NHQELTATQH TSKTLLVSMF NTQYDVSAAA
QITPMIVYQI FGNYGSVQKI VVLPKNESSQ RNHNRVQALV QFDSKVTAEN VKSILQGQPV
TIGDTVTFTL DIQFSRMDDI KTSNPAISLV INEDGVPQPP QPPQPPMAPP PPPPPPAPQQ
QPHPSPQQQQ VQGGNMYPVI PQQWS
//
