ID Q4DJ22_TRYCC Unreviewed; 729 AA.
AC Q4DJ22;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=DNA excision/repair protein SNF2, putative {ECO:0000313|EMBL:EAN92522.1};
GN ORFNames=Tc00.1047053504797.70 {ECO:0000313|EMBL:EAN92522.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN92522.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN92522.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN92522.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN92522.1}.
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DR EMBL; AAHK01000428; EAN92522.1; -; Genomic_DNA.
DR RefSeq; XP_814373.1; XM_809280.1.
DR AlphaFoldDB; Q4DJ22; -.
DR SMR; Q4DJ22; -.
DR STRING; 353153.Q4DJ22; -.
DR PaxDb; 353153-Q4DJ22; -.
DR EnsemblProtists; EAN92522; EAN92522; Tc00.1047053504797.70.
DR GeneID; 3545894; -.
DR KEGG; tcr:504797.70; -.
DR eggNOG; KOG0387; Eukaryota.
DR InParanoid; Q4DJ22; -.
DR OMA; MDDGEQR; -.
DR OrthoDB; 5485325at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45629:SF7; DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED; 1.
DR PANTHER; PTHR45629; SNF2/RAD54 FAMILY MEMBER; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..729
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004237206"
FT DOMAIN 104..270
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 421..575
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 649..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 729 AA; 81686 MW; D838F2DFE6AF87DC CRC64;
MLSFVCLFAC LLAFSIIHTI RRNSKTMNDE ELEELFSISH YTTITPTPTA KLRENDSINT
IRIDSSRKKT ASSAAIPLPE TLPISPEIEL KLFDYQREGV QWLYERHRKG RGCLLADEMG
LGKTVQIASF VGALYMSQLV TSTIIVVPPT LLPIWGLALQ QWGRLGPPVV EVIHNDAKNK
RLQRWQRLKH GTPCLFLTTY GVLRQDSSAM GVRMVDYVIM DEAHLIKDAS THVFQSAMAL
SARHRIAITG TPLMNNFEDL WSIFHFIDGS ILGTTRADFR SINAVLLRGN ERDALENERG
DAGRQLALIQ AAIRPFMLRR DKRQLQMLRV GKRDLIIWLR LNDTQEQQYF SFLKTERVDV
TLRSADTSQP LVLLTSLMRT CDHPWLSLSD EAYREAMQNP LASPEANRSC GDALNSSKIS
SALALVVKCI GEQRKTLVFS RSKRLLDLLA VALRCWLIDF ARLDGDVPAE ERLKTVQGFN
QSERLLVCLL TTQVGGVGLT VEAASAVIIM DPSWNPSSDA QAIDRVHRIG QTRDVVVYRL
ITCGTVEEKV YRNQVFKVMA AKQGTSVREQ TGRGSAEFYR YFTRLQLRSM FDVGTLDQSE
TAAQLESLHP NAVCPEERAA LTSLPFVCDV SDNSCVHVEA VVETERGSDT SLTMSASRRC
GAKRRRPSSL SPSTSNECRH ELLSQEEMSE ILLQLEEENT ESQSTTVQLV LTSEDTTTVT
ASPVDNSEV
//
