ID Q4DV83_TRYCC Unreviewed; 123 AA.
AC Q4DV83;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Autophagy-related protein {ECO:0000256|RuleBase:RU004384};
GN ORFNames=Tc00.1047053508173.47 {ECO:0000313|EMBL:EAN96431.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN96431.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN96431.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN96431.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- SIMILARITY: Belongs to the ATG8 family. {ECO:0000256|ARBA:ARBA00007293,
CC ECO:0000256|RuleBase:RU004384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN96431.1}.
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DR EMBL; AAHK01000153; EAN96431.1; -; Genomic_DNA.
DR RefSeq; XP_818282.1; XM_813189.1.
DR AlphaFoldDB; Q4DV83; -.
DR SMR; Q4DV83; -.
DR STRING; 353153.Q4DV83; -.
DR PaxDb; 353153-Q4DV83; -.
DR EnsemblProtists; EAN96431; EAN96431; Tc00.1047053508173.47.
DR GeneID; 3550478; -.
DR KEGG; tcr:508173.47; -.
DR eggNOG; KOG1654; Eukaryota.
DR InParanoid; Q4DV83; -.
DR OMA; AKMKWMF; -.
DR OrthoDB; 652940at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR InterPro; IPR004241; Atg8-like.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10969:SF100; AUTOPHAGY-RELATED PROTEIN 8F; 1.
DR PANTHER; PTHR10969; MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED; 1.
DR Pfam; PF02991; ATG8; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|RuleBase:RU004384};
KW Lipoprotein {ECO:0000256|PIRSR:PIRSR604241-50};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 121
FT /note="Phosphatidylserine amidated glycine; alternate"
FT /evidence="ECO:0000256|PIRSR:PIRSR604241-50"
SQ SEQUENCE 123 AA; 13966 MW; 51D8B3E1157DA745 CRC64;
MAPKKLESKY KKTHTLESRQ KEAAKVRERH PDRLPIICEK VDDSDIGDLD KGKFLVPSDL
TVGQFVLVLR KRVRVDADEA IFLFVNGAVP PTTAQMSDLY AHHKDEDGFL YIKYSGEATF
GSW
//
