ID Q4DXD8_TRYCC Unreviewed; 371 AA.
AC Q4DXD8;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 08-NOV-2023, entry version 82.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=Tc00.1047053508879.200 {ECO:0000313|EMBL:EAN97204.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN97204.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN97204.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN97204.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN97204.1}.
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DR EMBL; AAHK01000110; EAN97204.1; -; Genomic_DNA.
DR RefSeq; XP_819055.1; XM_813962.1.
DR AlphaFoldDB; Q4DXD8; -.
DR SMR; Q4DXD8; -.
DR PaxDb; 353153-Q4DXD8; -.
DR EnsemblProtists; EAN97204; EAN97204; Tc00.1047053508879.200.
DR GeneID; 3551411; -.
DR KEGG; tcr:508879.200; -.
DR eggNOG; ENOG502SB2N; Eukaryota.
DR InParanoid; Q4DXD8; -.
DR OMA; HGRIAHY; -.
DR OrthoDB; 165062at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR CDD; cd16448; RING-H2; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 107..148
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 26..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 210..258
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 287..314
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 332..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 371 AA; 41514 MW; DA0C08B84C673830 CRC64;
MFLFDAMRHA ECSICLQALI PGTGSSASPS NAISPEKKLP SPPRVSPAPQ LGEVSSGEEE
FRITFAPGVS RQDDTDDFMT FINALDMYHR AAKKNGSRHR TSREVGCGVT PCGADHGIVV
LPCGHLLHFL CAIQLHEYSN HPTCPICREA IKSPEDCVLF LPLSRPTVFQ RGMAVDGEVN
ACDISRTDED GGDNVQFTGE GSVAPADVYR RHIQHELDEL KRRRRNLRSR EHFLTNSRDQ
LEEQCISLEQ SASDARLRYD VLTRQGTVGL DRLKELRDVA LKTHTSMDQL TLELARLLRQ
QRDLDQQLEK YSQRLKRGRL SGQGIHSGSE GGGITRDDDN DDDLPFSLQK RRLKAPMAGV
PFSYYVSRDK K
//
