ID   Q4G679_9REOV            Unreviewed;       127 AA.
AC   Q4G679;
DT   30-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2005, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=NSP4 {ECO:0000313|EMBL:AAR18267.1};
DE   Flags: Fragment;
OS   Human rotavirus A.
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Sedoreoviridae; Rotavirus; Rotavirus A.
OX   NCBI_TaxID=10941 {ECO:0000313|EMBL:AAR18267.1};
RN   [1] {ECO:0000313|EMBL:AAR18267.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=A_G2_245 {ECO:0000313|EMBL:AAR18267.1};
RA   Szabo Zs., Matson D.O., Afflerbach C., Campos F., Berke T., Pickering L.K.,
RA   Ruiz-Palacios G.;
RT   "Sequence Differences of Rotavirus NSP4 Genes Between Strains From Human
RT   Symptomatic and Asymptomatic First Infections.";
RL   Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AY353723; AAR18267.1; -; Genomic_RNA.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.430; -; 1.
DR   InterPro; IPR002107; Rotavirus_NSP4.
DR   Pfam; PF01452; Rota_NSP4; 1.
DR   SUPFAM; SSF58030; Rotavirus nonstructural proteins; 1.
PE   4: Predicted;
KW   Activation of host autophagy by virus {ECO:0000256|ARBA:ARBA00023050};
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Enterotoxin {ECO:0000256|ARBA:ARBA00022861};
KW   Host-virus interaction {ECO:0000256|ARBA:ARBA00023050};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Toxin {ECO:0000256|ARBA:ARBA00022656}.
FT   COILED          37..64
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAR18267.1"
FT   NON_TER         127
FT                   /evidence="ECO:0000313|EMBL:AAR18267.1"
SQ   SEQUENCE   127 AA;  14869 MW;  FE364850A0DF088D CRC64;
     ASIPTMKIAL KTSKCSYKVV KYCIVTIFNT LLTLAGYKEQ ITTKDEIEKQ MDRVVKEMRR
     QLEMIDKLTT REIEQVELLK RIYDKLMVRS TGEIDMAKEI NQKNVRTLEE WEDGKNPYES
     KEVTAAM
//