ID Q4H034_ENTFC Unreviewed; 226 AA.
AC Q4H034;
DT 30-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2005, sequence version 1.
DT 13-SEP-2023, entry version 63.
DE SubName: Full=DNA-directed RNA polymerase alpha chain {ECO:0000313|EMBL:CAH59026.1};
DE EC=2.7.7.6 {ECO:0000313|EMBL:CAH59026.1};
DE Flags: Fragment;
GN Name=rpoA {ECO:0000313|EMBL:CAH59026.1};
OS Enterococcus faecium (Streptococcus faecium).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1352 {ECO:0000313|EMBL:CAH59026.1};
RN [1] {ECO:0000313|EMBL:CAH59026.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LMG 16270 {ECO:0000313|EMBL:CAH59018.1}, and LMG 20721
RC {ECO:0000313|EMBL:CAH59026.1};
RX PubMed=15872246; DOI=10.1128/JCM.43.5.2224-2230.2005;
RA Naser S., Thompson F.L., Hoste B., Gevers D., Vandemeulebroecke K.,
RA Cleenwerck I., Thompson C.C., Vancanneyt M., Swings J.;
RT "Phylogeny and identification of Enterococci by atpA gene sequence
RT analysis.";
RL J. Clin. Microbiol. 43:2224-2230(2005).
RN [2] {ECO:0000313|EMBL:CAH59026.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LMG 16270 {ECO:0000313|EMBL:CAH59018.1}, and LMG 20721
RC {ECO:0000313|EMBL:CAH59026.1};
RA Naser S., Thompson F., Hoste B., Gevers D., Dawyndt P., Vancanneyt M.,
RA Swings J.;
RT "Application of multilocus sequence analysis (MLSA) for rapid
RT identificationof Enterococcus species based on rpoA and pheS genes.";
RL Microbiology (Mosc.) 151:2141-2150(2005).
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DR EMBL; AJ843541; CAH59018.1; -; Genomic_DNA.
DR EMBL; AJ843549; CAH59026.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4H034; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd06928; RNAP_alpha_NTD; 1.
DR Gene3D; 2.170.120.12; DNA-directed RNA polymerase, insert domain; 1.
DR Gene3D; 3.30.1360.10; RNA polymerase, RBP11-like subunit; 1.
DR InterPro; IPR011262; DNA-dir_RNA_pol_insert.
DR InterPro; IPR011263; DNA-dir_RNA_pol_RpoA/D/Rpb3.
DR InterPro; IPR011773; DNA-dir_RpoA.
DR InterPro; IPR036603; RBP11-like.
DR InterPro; IPR036643; RNApol_insert_sf.
DR NCBIfam; TIGR02027; rpoA; 1.
DR Pfam; PF01000; RNA_pol_A_bac; 1.
DR Pfam; PF01193; RNA_pol_L; 1.
DR SMART; SM00662; RPOLD; 1.
DR SUPFAM; SSF56553; Insert subdomain of RNA polymerase alpha subunit; 1.
DR SUPFAM; SSF55257; RBP11-like subunits of RNA polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000313|EMBL:CAH59026.1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:CAH59026.1};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000313|EMBL:CAH59026.1}.
FT DOMAIN 1..205
FT /note="DNA-directed RNA polymerase RpoA/D/Rpb3-type"
FT /evidence="ECO:0000259|SMART:SM00662"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAH59026.1"
FT NON_TER 226
FT /evidence="ECO:0000313|EMBL:CAH59026.1"
SQ SEQUENCE 226 AA; 25213 MW; 7D040E7132DBE7E2 CRC64;
FIVEPLERGY GTTLGNSLRR ILLSSLPGAA ITNIQIDGVL HEFSTIKGVR EDVTQIILNI
KGLALKMYGQ EEKTLEIDIT GPATVTAGDI IVDSDVEILN KDMYICSVSE GATFHARLTV
KPGRGYVQAD ENKKEDMPIG VLPVDSIYTP VRRVNYQVEN TRVGHREDFD KLTMEIWTDG
SIEPLEAMSL SAKIMTEHLD IFVNLTDEAK NAEIMVEKEE TQKEKM
//
