ID   Q4JNW2_ARATH            Unreviewed;       392 AA.
AC   Q4JNW2;
DT   02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   02-AUG-2005, sequence version 1.
DT   22-FEB-2023, entry version 72.
DE   SubName: Full=Chalcone synthase family protein {ECO:0000313|EMBL:AAY96725.1};
DE   Flags: Fragment;
GN   OrderedLocusNames=At1g02050 {ECO:0000313|EMBL:AAY96725.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000313|EMBL:AAY96725.1};
RN   [1] {ECO:0000313|EMBL:AAY96725.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Chiang T.-Y., Wang W.-K.;
RT   "Diverse selective modes among orthologs/ paralogs of the chalcone synthase
RT   (Chs) gene family of Arabidopsis thaliana and its relative Arabidopsis
RT   halleri subsp. gemmifera.";
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC       ECO:0000256|RuleBase:RU003633}.
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DR   EMBL; DQ062317; AAY96725.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4JNW2; -.
DR   ExpressionAtlas; Q4JNW2; baseline and differential.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW   Transferase {ECO:0000256|RuleBase:RU003633}.
FT   DOMAIN          14..236
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          245..392
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        172
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
FT   NON_TER         392
FT                   /evidence="ECO:0000313|EMBL:AAY96725.1"
SQ   SEQUENCE   392 AA;  43270 MW;  9B8C590463EC608E CRC64;
     MSNSRMNGVE KLSSKSTRRV ANAGKATLLA LGKAFPSQVV PQENLVEGFL RDTKCDDAFI
     KEKLEHLCKT TTVKTRYTVL TREILAKYPE LTTEGSPTIK QRLEIANEAV VEMALEASLG
     CIKEWGRPVE DITHIVYVSS SEIRLPGGDL YLSAKLGLRN DVNRVMLYFL GCYGGVTGLR
     VAKDIAENNP GSRVLLTTSE TTILGFRPPN KARPYDLVGA ALFGDGAAAV IIGADPRECE
     APFMELHYAV QQFLPGTQNV IEGRLTEEGI NFKLGRDLPQ KIEENIEEFC KKLMGKAGDG
     SMEFNDMFWA VHPGGPAILN RLETKLKLEK EKLESSRRAL VDYGNVSSNT ILYVMEYMRD
     ELKKKGDAAQ EWGLGLAFGP GITFEGLLIR SL
//