ID   Q4JZK8_STREE            Unreviewed;       370 AA.
AC   Q4JZK8;
DT   02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   02-AUG-2005, sequence version 1.
DT   13-SEP-2023, entry version 62.
DE   SubName: Full=UDP-galactopyranose mutase Glf {ECO:0000313|EMBL:CAI34219.1};
DE            EC=5.4.99.9 {ECO:0000313|EMBL:CAI34219.1};
GN   Name=glf {ECO:0000313|EMBL:CAI34219.1};
GN   ORFNames=SPC33C_0016 {ECO:0000313|EMBL:CAI34219.1};
OS   Streptococcus pneumoniae.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1313 {ECO:0000313|EMBL:CAI34219.1};
RN   [1] {ECO:0000313|EMBL:CAI34219.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=7098/41 {ECO:0000313|EMBL:CAI34219.1};
RX   PubMed=16532061; DOI=10.1371/journal.pgen.0020031;
RA   Bentley S.D., Aanensen D.M., Mavroidi A., Saunders D., Rabbinowitsch E.,
RA   Collins M., Donohoe K., Harris D., Murphy L., Quail M.A., Samuel G.,
RA   Skovsted I.C., Kaltoft M.S., Barrell B., Reeves P.R., Parkhill J.,
RA   Spratt B.G.;
RT   "Genetic analysis of the capsular biosynthetic locus from all 90
RT   pneumococcal serotypes.";
RL   PLoS Genet. 2:262-268(2006).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase
CC       family. {ECO:0000256|ARBA:ARBA00009321}.
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DR   EMBL; CR931700; CAI34219.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4JZK8; -.
DR   GO; GO:0008767; F:UDP-galactopyranose mutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 3.
DR   InterPro; IPR004379; UDP-GALP_mutase.
DR   InterPro; IPR015899; UDP-GalPyranose_mutase_C.
DR   NCBIfam; TIGR00031; UDP-GALP_mutase; 1.
DR   PANTHER; PTHR21197; UDP-GALACTOPYRANOSE MUTASE; 1.
DR   PANTHER; PTHR21197:SF0; UDP-GALACTOPYRANOSE MUTASE; 1.
DR   Pfam; PF03275; GLF; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:CAI34219.1}.
FT   DOMAIN          150..350
FT                   /note="UDP-galactopyranose mutase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03275"
SQ   SEQUENCE   370 AA;  43109 MW;  2D509DA5BEFF911F CRC64;
     MELTMYDYLI VGAGLSGAIF AHEATKRGKK VKVIDKRDHI GGNIYCENVE GINVHKYGAH
     IFHTSNKKVW DYVNQFTEFN NYINSPVANY KGSLYNLPFN MNTFYAMWGT KTPQEVKNKI
     AQQTANMKDV EPKNLEEQAI KLIGPDIYEK LIKGYTEKQW GRSATDLPPF IIKRLPVRLT
     FDNNYFNDRY QGIPIGGYNV IIENMLGDVE VELGVDFFAN REELEASAEK VVFTGMIDQY
     FDYKHGELEY RSLRFEHEAL DEENYQGNAV VNYTEREIPY TRIIEHKHFE YGTQPKTVIT
     REYPADWKRG DEPYYPINDE RNNAMFAKYQ EEAAKNDKVI FCGRLADYKY YDMHVVIERA
     LEVVLSELGK
//