ID Q4KKH9_PSEF5 Unreviewed; 460 AA.
AC Q4KKH9;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Peptidase, M16 family {ECO:0000313|EMBL:AAY95519.1};
DE EC=3.4.24.- {ECO:0000313|EMBL:AAY95519.1};
GN OrderedLocusNames=PFL_0102 {ECO:0000313|EMBL:AAY95519.1};
OS Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=220664 {ECO:0000313|EMBL:AAY95519.1, ECO:0000313|Proteomes:UP000008540};
RN [1] {ECO:0000313|EMBL:AAY95519.1, ECO:0000313|Proteomes:UP000008540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-477 / NRRL B-23932 / Pf-5
RC {ECO:0000313|Proteomes:UP000008540};
RX PubMed=15980861; DOI=10.1038/nbt1110;
RA Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.,
RA Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J.,
RA Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A., Rosovitz M.J.,
RA Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W., Nelson W.C.,
RA Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A., Pierson L.S.III.,
RA Thomashow L.S., Loper J.E.;
RT "Complete genome sequence of the plant commensal Pseudomonas fluorescens
RT Pf-5.";
RL Nat. Biotechnol. 23:873-878(2005).
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261}.
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DR EMBL; CP000076; AAY95519.1; -; Genomic_DNA.
DR RefSeq; WP_011058489.1; NC_004129.6.
DR AlphaFoldDB; Q4KKH9; -.
DR STRING; 220664.PFL_0102; -.
DR KEGG; pfl:PFL_0102; -.
DR PATRIC; fig|220664.5.peg.106; -.
DR eggNOG; COG0612; Bacteria.
DR HOGENOM; CLU_592957_0_0_6; -.
DR Proteomes; UP000008540; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AAY95519.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..460
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004240332"
FT TRANSMEM 434..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..148
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 189..362
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 460 AA; 51484 MW; 2E6639E3EB917CD0 CRC64;
MRCLLFACLL LGSAQGWALD RFQVEGYTLP NGLQLLLKPG SERGHVAIRL VVGVGLDDFA
CADKELPHLL EHLLFSGVDD SGEGGLEERM QALGGEWNAY TSNADTTFVI EAPARNQRKV
LDLLLSLLTH TRLDDNAVAA AKQVVEREGG GHYSHLQRWL DRQDLGHKAG NQLAVELGLK
CAERAEVGNL TLAQLEQVRK DWYAPNNMTL IVVGELDRLL PAYLERTYGA LEPVEPSEHP
DLPQIQGTAA PERTLVHGWV GQSAQLHWLF PEPVLDQQHD ETFDLLKDYL DWALYRQLRL
EHELSYGPWS DREVFGGVGF LSLNADLERD DLPQARQVVE QLKARLLKDG LDPATFARLK
QAAIDRQAWA VQGNSALADY YWSALGDFDN GRFSDPAKRL KAVSLEQANL ALRQLLQQPG
YLRIEQPLLS DEQLLWLIGG LLSLILLGSF GVYLLRRRAR
//
