ID Q4N9G3_THEPA Unreviewed; 518 AA.
AC Q4N9G3;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Biquinol-cytochrome C reductase complex core protein I, mitochondrial, putative {ECO:0000313|EMBL:EAN33395.1};
DE EC=1.10.2.2 {ECO:0000313|EMBL:EAN33395.1};
GN OrderedLocusNames=TP01_0151 {ECO:0000313|EMBL:EAN33395.1};
OS Theileria parva (East coast fever infection agent).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=5875 {ECO:0000313|EMBL:EAN33395.1, ECO:0000313|Proteomes:UP000001949};
RN [1] {ECO:0000313|EMBL:EAN33395.1, ECO:0000313|Proteomes:UP000001949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Muguga {ECO:0000313|EMBL:EAN33395.1,
RC ECO:0000313|Proteomes:UP000001949};
RX PubMed=15994558; DOI=10.1126/science.1110439;
RA Gardner M.J., Bishop R., Shah T., de Villiers E.P., Carlton J.M., Hall N.,
RA Ren Q., Paulsen I.T., Pain A., Berriman M., Wilson R.J.M., Sato S.,
RA Ralph S.A., Mann D.J., Xiong Z., Shallom S.J., Weidman J., Jiang L.,
RA Lynn J., Weaver B., Shoaibi A., Domingo A.R., Wasawo D., Crabtree J.,
RA Wortman J.R., Haas B., Angiuoli S.V., Creasy T.H., Lu C., Suh B.,
RA Silva J.C., Utterback T.R., Feldblyum T.V., Pertea M., Allen J.,
RA Nierman W.C., Taracha E.L.N., Salzberg S.L., White O.R., Fitzhugh H.A.,
RA Morzaria S., Venter J.C., Fraser C.M., Nene V.;
RT "Genome sequence of Theileria parva, a bovine pathogen that transforms
RT lymphocytes.";
RL Science 309:134-137(2005).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|RuleBase:RU004447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN33395.1}.
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DR EMBL; AAGK01000001; EAN33395.1; -; Genomic_DNA.
DR RefSeq; XP_765678.1; XM_760585.1.
DR AlphaFoldDB; Q4N9G3; -.
DR STRING; 5875.Q4N9G3; -.
DR MEROPS; M16.003; -.
DR EnsemblProtists; EAN33395; EAN33395; TP01_0151.
DR GeneID; 3502885; -.
DR KEGG; tpv:TP01_0151; -.
DR VEuPathDB; PiroplasmaDB:TpMuguga_01g00151; -.
DR eggNOG; KOG0960; Eukaryota.
DR InParanoid; Q4N9G3; -.
DR OMA; IDVVCDM; -.
DR Proteomes; UP000001949; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851:SF149; GH01077P; 1.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:EAN33395.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001949}.
FT DOMAIN 83..228
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 235..433
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 518 AA; 58766 MW; BD2705E4BE26BB2F CRC64;
MGVFSKIGRV SPDVSTLIVN KCARRTLFTN RHNYVSNPRF NLTLKRNVTT SLATDLFKDS
KLHPNALNQP PCHVTTLKNG LRVATVWMPG SSSTVGVWID SGSRFETPET NGSAHFLEHM
IFKGTKSRSR HQLEEQIEHK GAHLNAYTSR EQTAYYARCF NNDIPWCTEL LSDILQNSLI
DPDHMENEKH VILREMEEVE KSHDEVVFDR LHMTAFRDCS LGFTILGPVE NIKNMQREYL
LDYINRNYTA DRMVFYTPII ISQVLCAVGN FEHDKFVSLA EKHFSTIPKA VTKVELEKPY
FVGSELLERN DEMGPYAHIA VALEGVPWNS PDSVAFMLMQ SIIGTYNKSN EGVVPGKVSG
NKTIHAVANR MTVGCAEFFS AFNTCYKDTG LFGFYAKADE VAVDHCVGEL LFGITSLSYS
VTDEEVERAK RQLMLQFLSM TESTSSVAEE VARQILVYGR RMPVAEFLLR LEKIDAEEVK
RVAWKYLHDS EVAVSAMGPL HGMPSLVDLR QKTYWLRY
//
