ID Q4Q8I6_LEIMA Unreviewed; 142 AA.
AC Q4Q8I6;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Putative RNA binding protein rbp16 {ECO:0000313|EMBL:CAJ05173.1};
GN ORFNames=LMJF_28_0825 {ECO:0000313|EMBL:CAJ05173.1};
OS Leishmania major.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5664 {ECO:0000313|EMBL:CAJ05173.1, ECO:0000313|Proteomes:UP000000542};
RN [1] {ECO:0000313|EMBL:CAJ05173.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=16020728; DOI=10.1126/science.1112680;
RA Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G.,
RA Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A.,
RA Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M.,
RA Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E.,
RA Ciarloni L., Clayton C., Coulson R.M., Cronin A., Cruz A.K., Davies R.M.,
RA De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N.,
RA Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A.,
RA Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S.,
RA Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M.,
RA Masuy D., Matthews K., Michaeli S., Mottram J.C., Muller-Auer S.,
RA Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M.,
RA Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E.,
RA Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C.,
RA Rutter S., Saunders D., Schafer M., Schein J., Schwartz D.C., Seeger K.,
RA Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V.,
RA Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J.,
RA Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D.,
RA Barrell B., Myler P.J.;
RT "The genome of the kinetoplastid parasite, Leishmania major.";
RL Science 309:436-442(2005).
RN [2] {ECO:0000313|EMBL:CAJ05173.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796424; CAJ05173.1; -; Genomic_DNA.
DR RefSeq; XP_001684362.1; XM_001684310.1.
DR AlphaFoldDB; Q4Q8I6; -.
DR STRING; 5664.Q4Q8I6; -.
DR EnsemblProtists; CAJ05173; CAJ05173; LMJF_28_0825.
DR GeneID; 5653290; -.
DR KEGG; lma:LMJF_28_0825; -.
DR VEuPathDB; TriTrypDB:LmjF.28.0825; -.
DR VEuPathDB; TriTrypDB:LMJFC_280014600; -.
DR VEuPathDB; TriTrypDB:LMJLV39_280014200; -.
DR VEuPathDB; TriTrypDB:LMJSD75_280014200; -.
DR eggNOG; KOG3070; Eukaryota.
DR HOGENOM; CLU_1829283_0_0_1; -.
DR InParanoid; Q4Q8I6; -.
DR OMA; GKVVSWM; -.
DR Proteomes; UP000000542; Chromosome 28.
DR GO; GO:0005737; C:cytoplasm; ISO:GeneDB.
DR GO; GO:0005730; C:nucleolus; ISO:GeneDB.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd04458; CSP_CDS; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR011129; CSD.
DR InterPro; IPR002059; CSP_DNA-bd.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR46565; COLD SHOCK DOMAIN PROTEIN 2; 1.
DR PANTHER; PTHR46565:SF20; COLD SHOCK PROTEIN 2; 1.
DR Pfam; PF00313; CSD; 1.
DR SMART; SM00357; CSP; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS51857; CSD_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000542}.
FT DOMAIN 17..84
FT /note="CSD"
FT /evidence="ECO:0000259|PROSITE:PS51857"
FT REGION 71..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 142 AA; 15141 MW; 61DFB0A85D2B80F5 CRC64;
MFRVSSVSRI APSLALLNTG KVVSWMSGRG FGFIEDNADK KQHFVHFSAL QTETGGYRAL
AVDQEVEFEV ASQDGRTRAE NVTAPGGGKL PSGPRPPEGS PSGRGGFGGG RGRGRGGRNN
NRQDRGGDRD GGRQNNNFSD EF
//
