ID Q4R8W7_MACFA Unreviewed; 327 AA.
AC Q4R8W7;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Testis cDNA clone: QtsA-11283, similar to human coatomer protein complex, subunit beta (COPB) {ECO:0000313|EMBL:BAE00454.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|EMBL:BAE00454.1};
RN [1] {ECO:0000313|EMBL:BAE00454.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15944441; DOI=10.1093/molbev/msi187;
RA Osada N., Hirata M., Tanuma R., Kusuda J., Hida M., Suzuki Y., Sugano S.,
RA Gojobori T., Shen C.K., Wu C.I., Hashimoto K.;
RT "Substitution rate and structural divergence of 5'UTR evolution:
RT comparative analysis between human and cynomolgus monkey cDNAs.";
RL Mol. Biol. Evol. 22:1976-1982(2005).
RN [2] {ECO:0000313|EMBL:BAE00454.1}
RP NUCLEOTIDE SEQUENCE.
RG International consortium for macaque cDNA sequencing and analysis;
RT "DNA sequences of macaque genes expressed in brain or testis and its
RT evolutionary implications.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPI-coated vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004347}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004347}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004347}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004255}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; AB168330; BAE00454.1; -; mRNA.
DR AlphaFoldDB; Q4R8W7; -.
DR GO; GO:0030126; C:COPI vesicle coat; IEA:InterPro.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR011710; Coatomer_bsu_C.
DR InterPro; IPR016460; COPB1.
DR InterPro; IPR029446; COPB1_appendage_platform_dom.
DR PANTHER; PTHR10635; COATOMER SUBUNIT BETA; 1.
DR PANTHER; PTHR10635:SF0; COATOMER SUBUNIT BETA; 1.
DR Pfam; PF07718; Coatamer_beta_C; 1.
DR Pfam; PF14806; Coatomer_b_Cpla; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 41..180
FT /note="Coatomer beta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07718"
FT DOMAIN 187..318
FT /note="Coatomer beta subunit appendage platform"
FT /evidence="ECO:0000259|Pfam:PF14806"
FT REGION 25..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 36265 MW; CE5509F398F2B280 CRC64;
MNDIFNKECR QSLSHMLSAK LEEEKLSQKK ESEKRNVTVQ PDDPTSFMQL TAKNEMNCKE
DQFQLSLLAA MGNTQRKEAA DPLASKLNKV TQLTGFSDPV YAEAYVHVNQ YDIVLDVLVV
NQTSDTLQNC TLELATLGDL KLVEKPSPLT LAPHDFANIK ANVKVASTEN GIIFGNIVYD
VSGAASDRNC VVLSDIHIDI MDYIQPATCT DAEFRQMWAE FEWENKVTVN TNMIDLNDYL
QHILKSTNMK CLTPEKALSG YCGFMAANLY AHSIFGEDAL ANVSIEKPIH QGPDAAVTGH
IRIRAKSQGM ALSLGDKINL SQKKTSI
//
