ID   Q4TTF4_CAERE            Unreviewed;       474 AA.
AC   Q4TTF4;
DT   19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   19-JUL-2005, sequence version 1.
DT   24-JAN-2024, entry version 64.
DE   SubName: Full=Importin alpha subunit {ECO:0000313|EMBL:AAY54266.1};
DE   Flags: Fragment;
OS   Caenorhabditis remanei (Caenorhabditis vulgaris).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=31234 {ECO:0000313|EMBL:AAY54266.1};
RN   [1] {ECO:0000313|EMBL:AAY54266.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EM464 {ECO:0000313|EMBL:AAY54266.1};
RA   Mento S.C., Nemeroff M.E.;
RT   "Isolation of a mRNA for importin protein alpha subunit from Caenorhabditis
RT   remanei.";
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the importin alpha family.
CC       {ECO:0000256|ARBA:ARBA00010394}.
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DR   EMBL; DQ072249; AAY54266.1; -; mRNA.
DR   AlphaFoldDB; Q4TTF4; -.
DR   HOGENOM; CLU_018084_6_0_1; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblMetazoa.
DR   GO; GO:0005643; C:nuclear pore; IEA:EnsemblMetazoa.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IEA:EnsemblMetazoa.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:EnsemblMetazoa.
DR   GO; GO:0007127; P:meiosis I; IEA:EnsemblMetazoa.
DR   GO; GO:0002119; P:nematode larval development; IEA:EnsemblMetazoa.
DR   GO; GO:0006999; P:nuclear pore organization; IEA:EnsemblMetazoa.
DR   GO; GO:0048477; P:oogenesis; IEA:EnsemblMetazoa.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:EnsemblMetazoa.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR032413; Arm_3.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR024931; Importin_alpha.
DR   PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR   PANTHER; PTHR23316:SF28; IMPORTIN SUBUNIT ALPHA; 1.
DR   Pfam; PF00514; Arm; 7.
DR   Pfam; PF16186; Arm_3; 1.
DR   PIRSF; PIRSF005673; Importin_alpha; 1.
DR   SMART; SM00185; ARM; 8.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
PE   2: Evidence at transcript level;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   REPEAT          69..111
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAY54266.1"
SQ   SEQUENCE   474 AA;  51483 MW;  FA364BBD8AED9EC4 CRC64;
     KRRNINAHIE DDSETSTTPP GPFDANLLRL TVAAAQSTDP AEQLTAVQQA RKMLSTDRNP
     PIDDLIGSGI LPVLVQCLSS TDPNLQFEAA WALTNIASGT SEQTQAVVNA GAVPLFLQLL
     SCGNLNVCEQ SVWALGNIIG DGPHFRDYCL ELGILQPLLQ FINPEIPIGF LRNVTWVIVN
     LCRCKDPAPS PAVVRTILPA LSLLIHHQDT NILIDTVWAL SYLTDGGNEH IQMVIEAQVV
     THLVPLLGHV DVKVQTAALR AVGNIVTGTD EQTQLVLDSG VLRFMPGLLA HYKEKINKEA
     VWFVSNITAG NQQQVQDVFD AGIMPMIIHL LDRGDFPTQK EAAWAISNVT ISGRPNQVEQ
     MVKLGVLRPF CAMLSCTDSQ IIQVVLDGIN NILKMAGEAA EQVTSEIEEC GGLDKIENLQ
     NHENEDIYKL AFEIIDNFFS SDDEAGNVEG APNQFGGDVP PVPDAPNGGW DFGK
//