ID Q4UEH9_THEAN Unreviewed; 657 AA.
AC Q4UEH9;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=RNA processing protein (Crooked neck family), putative {ECO:0000313|EMBL:CAI74510.1};
GN ORFNames=TA13380 {ECO:0000313|EMBL:CAI74510.1};
OS Theileria annulata.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=5874 {ECO:0000313|EMBL:CAI74510.1, ECO:0000313|Proteomes:UP000001950};
RN [1] {ECO:0000313|EMBL:CAI74510.1, ECO:0000313|Proteomes:UP000001950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ankara {ECO:0000313|Proteomes:UP000001950};
RX PubMed=15994557; DOI=10.1126/science.1110418;
RA Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W.,
RA Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R.,
RA Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A.,
RA Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P.,
RA McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D.,
RA Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R.,
RA Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D.,
RA Shiels B., Tait A., Barrell B.G., Hall N.;
RT "Genome of the host-cell transforming parasite Theileria annulata compared
RT with T. parva.";
RL Science 309:131-133(2005).
CC -!- FUNCTION: Involved in pre-mRNA splicing and cell cycle progression.
CC Required for the spliceosome assembly and initiation of the DNA
CC replication. {ECO:0000256|ARBA:ARBA00037040}.
CC -!- SUBUNIT: Associated with the spliceosome.
CC {ECO:0000256|ARBA:ARBA00011524}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the crooked-neck family.
CC {ECO:0000256|ARBA:ARBA00008644}.
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DR EMBL; CR940348; CAI74510.1; -; Genomic_DNA.
DR RefSeq; XP_952242.1; XM_947149.1.
DR AlphaFoldDB; Q4UEH9; -.
DR STRING; 5874.Q4UEH9; -.
DR GeneID; 3861565; -.
DR KEGG; tan:TA13380; -.
DR VEuPathDB; PiroplasmaDB:TA13380; -.
DR eggNOG; KOG1915; Eukaryota.
DR InParanoid; Q4UEH9; -.
DR OMA; HIKVWIS; -.
DR OrthoDB; 5479069at2759; -.
DR Proteomes; UP000001950; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045075; Syf1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR11246:SF3; CROOKED NECK-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR11246; PRE-MRNA SPLICING FACTOR; 1.
DR Pfam; PF14559; TPR_19; 1.
DR SMART; SM00386; HAT; 15.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001950};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 73..106
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 657 AA; 79454 MW; 92DD0423F097C172 CRC64;
MPPFDPSKLQ VKNKMPAAVQ ITAEQILRDA VEWQTKEVKT TKQTIADEEE LNFYKAQKRK
EFEDTLRRQR HHIGTWIKYA VWEANQQEFR RARSIFERAL LVDPNNPSLW LRYIETEMKN
KNINSARNLF DRVVCLLPRI DQFWFKYAHF EELLGNYAGA RSIYERWMEW NPEDKAWMLY
IKFEERCGEL DRCRSIFNRY IENRPSCMSF LKLVKFEEKY KKVSRARSAF VKCVEVLDPE
LLDEDFFIKF ANFEQRQNNI EGANSVYEQG LKLLDKTKSE KLYDNFISFQ KQFKNEFIDD
LISVKKRNEY EGDIALNPDN YDTWFNYIKL EESILENMLK TCSDEKLEAQ KDRIVQVYER
AIANLPKDNN RKLWRRYSYL WIFYAFFSEL QLDSKERAEE IYLKSLQILP RDFSKIYIYL
SQLYLRMGDL KKMRSVMGNA IGLCKKEKIF ETYSDIELKL GNIDRCRIIF TKYVEIYPYN
YKSWLSYINF ELLLNEINRV RKLCEYAIEM EQMNNPEAIW NKYISIEKNY SYSNVISLYK
KLLQKTQHIK IYKEYSKYEY ENGNNEKGRE VIEEGIKLYK DSSVERSKLL YHLVEMEKKY
GNEQTVQNAK KRLPKKILRK RKLENDQEVD DIIYVFPDDK TNTKILENAL KWKKQQK
//
