ID Q4W291_9HYME Unreviewed; 282 AA.
AC Q4W291;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 13-SEP-2023, entry version 42.
DE SubName: Full=Virulence protein, P4 {ECO:0000313|EMBL:CAI28919.1};
DE Flags: Fragment;
GN Name=p4 {ECO:0000313|EMBL:CAI28919.1};
OS Leptopilina boulardi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Proctotrupomorpha;
OC Cynipoidea; Figitidae; Eucoilinae; Leptopilina.
OX NCBI_TaxID=63433 {ECO:0000313|EMBL:CAI28919.1};
RN [1] {ECO:0000313|EMBL:CAI28919.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=G431 {ECO:0000313|EMBL:CAI28919.1};
RX PubMed=15681220; DOI=10.1016/j.ibmb.2004.10.004;
RA Labrosse C., Stasiak K., Lesobre J., Grangeia A., Huguet E., Drezen J.M.,
RA Poirie M.;
RT "A RhoGAP protein as a main immune suppressive factor in the Leptopilina
RT boulardi (Hymenoptera, Figitidae)-Drosophila melanogaster interaction.";
RL Insect Biochem. Mol. Biol. 35:93-103(2005).
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DR EMBL; AJ866715; CAI28919.1; -; mRNA.
DR AlphaFoldDB; Q4W291; -.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04382; RhoGAP_MgcRacGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46199:SF3; FI24033P1-RELATED; 1.
DR PANTHER; PTHR46199; RAC GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 2: Evidence at transcript level;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..282
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004245256"
FT DOMAIN 37..224
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 241..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAI28919.1"
FT NON_TER 282
FT /evidence="ECO:0000313|EMBL:CAI28919.1"
SQ SEQUENCE 282 AA; 32133 MW; 121AF290F38A37DA CRC64;
MISLKEFFLL FFVTFSLVDG WPWEKTLNLG EESDTFGTIE KYTKGMKSLL VPYFVKNCIT
EVERRGLEEI GLYRVSGSKN NVENIIKTYR KKKNADLSKF NDINDITGAF KLFLRSMKGR
IIDVDLGKEL LLAIENLSPN LETELKEIIS KLPTPNIQTL AFIILHLQVV SRIPENEMNI
HSLAIVVAPS VFSDIGIAPE DSVEIIQSRI KIFEKLLEIP SDFWYELLRL NDNSEAMEDE
FSDTDSIIFE TDNEDEYEES KKKPSDEASL SSGISSDVSK IL
//
