ID Q4W528_CAEEL Unreviewed; 389 AA.
AC Q4W528;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 2.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=C-type lectin domain-containing protein {ECO:0000313|EMBL:CCD69843.1};
GN Name=clec-218 {ECO:0000313|EMBL:CCD69843.1,
GN ECO:0000313|WormBase:W02D7.2};
GN ORFNames=CELE_W02D7.2 {ECO:0000313|EMBL:CCD69843.1}, W02D7.2
GN {ECO:0000313|WormBase:W02D7.2};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD69843.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD69843.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD69843.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284605; CCD69843.1; -; Genomic_DNA.
DR RefSeq; NP_505147.3; NM_072746.6.
DR AlphaFoldDB; Q4W528; -.
DR SMR; Q4W528; -.
DR STRING; 6239.W02D7.2.1; -.
DR PaxDb; 6239-W02D7-2; -.
DR PeptideAtlas; Q4W528; -.
DR EnsemblMetazoa; W02D7.2.1; W02D7.2.1; WBGene00020938.
DR GeneID; 189114; -.
DR KEGG; cel:CELE_W02D7.2; -.
DR UCSC; W02D7.2; c. elegans.
DR AGR; WB:WBGene00020938; -.
DR WormBase; W02D7.2; CE41941; WBGene00020938; clec-218.
DR eggNOG; ENOG502TGZK; Eukaryota.
DR GeneTree; ENSGT00530000064644; -.
DR HOGENOM; CLU_060615_0_0_1; -.
DR InParanoid; Q4W528; -.
DR OMA; ECQCILN; -.
DR OrthoDB; 3773050at2759; -.
DR PhylomeDB; Q4W528; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00020938; Expressed in adult organism and 1 other cell type or tissue.
DR GO; GO:0050830; P:defense response to Gram-positive bacterium; IEP:WormBase.
DR CDD; cd00037; CLECT; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR31024; C-TYPE LECTIN; 1.
DR PANTHER; PTHR31024:SF9; C-TYPE LECTIN; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00034; CLECT; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q4W528};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..389
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004245891"
FT DOMAIN 38..226
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 250..368
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
SQ SEQUENCE 389 AA; 43994 MW; D5485F1B57DCB5F2 CRC64;
MRFFPVATIL FLAFCAVRCA EPNTEKECQC ILNNIWLDVY LLIDNSAKMG SVGLLEVASN
VNSVFGFTQI RVGSNYPDKR GARVSVLTYS DSPTVHANLS DFKSTDELTS MIYALKPSTS
YDSNLQSSLK LVKNMMNYKD INAPRNNTQT VIIIYAGDYV DYDEPTIAQF GDQLKADGVK
IITVADISNT DHQHVSKLKW LKELASEGNG FNINDDYVSE EVQKALCSAN CFCPRKYHHF
ITSNNETTHK YGTCVQFSIE QLSWTKAKFF CQNLHKQGYL ATEYTDEKHL FNEKYFEALS
SQPKPFKYHI GLHYVNGGYF WEQAIGIPLI PVSTPLYPLD NVPSTTQQCV RNIGTLDSED
LKWDNENCFN DVSPLMCEVP ACDTENYCP
//
