ID Q4W972_ASPFU Unreviewed; 769 AA.
AC Q4W972;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Kelch repeat protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AFUA_4G00490 {ECO:0000313|EMBL:EAL84369.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL84369.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL84369.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL84369.1}.
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DR EMBL; AAHF01000017; EAL84369.1; -; Genomic_DNA.
DR RefSeq; XP_746407.1; XM_741314.1.
DR AlphaFoldDB; Q4W972; -.
DR EnsemblFungi; EAL84369; EAL84369; AFUA_4G00490.
DR GeneID; 3503765; -.
DR KEGG; afm:AFUA_4G00490; -.
DR eggNOG; ENOG502SIX7; Eukaryota.
DR HOGENOM; CLU_012508_1_1_1; -.
DR InParanoid; Q4W972; -.
DR OMA; DRESWQP; -.
DR OrthoDB; 2358510at2759; -.
DR Proteomes; UP000002530; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd12087; TM_EGFR-like; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR PANTHER; PTHR46228; KELCH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46228:SF2; KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_4G14350); 1.
DR Pfam; PF13854; Kelch_5; 1.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..769
FT /note="Kelch repeat protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004245901"
FT TRANSMEM 524..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 679..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 769 AA; 83396 MW; 47C40CBF8A666267 CRC64;
MRFSWQRSAG ISALLVGCSL AQGWNVNVSM CNWDQVRGIL RPSCPSAAKA YMSQLVRFAT
LFTLTEGHCG GSGNSDGLLY YLNLNTSFDT AISNLTALFG NISKAGGIAN NIAPTYRDGA
MFTNDNELYL YGYFDSLFTN SRLTICSGLL RLTDSQDPPA GNTVLGYERY QYGPDRESWQ
PGFIIDNLDT GVTRYVTNGA GVSAPNENLG FYFSGMRGKD WGPIYADDKS ANVTSDRMIK
VDMSSMRHNK WSNLSLPAHV PARANGELVW VPVAESGVLV AIGGVINPAT IFSSDGLTSA
QQNASKRVSP GLMETVSVYD VSGDKWYLQN TTGDIPPQLT QFCSIHASAQ DGSSHNIYIY
GGYDGLSMEN TPSDDVYVLS LPSFSWIKLY SGNTTHGRSG HRCVKPYPDQ MLVLGGVHLD
PTHCLDGGVI QVFNLNTGRF QNTYNPNVWN EYKVPDLITT VIGGDSEGGA TKASPISWTN
ASLADVFKTK YTNTISTWYP YNSTSSISPT IAPAADKGSS FPKWASAIIG VILGFLFISA
AAIFWFLRRR HKLRESQSTG DRSTRSWILR WLHTSGSATG VPKSGDTTAP TGYSVFTNES
TITPATAVSP QSVEAGSDPV YEMLGQFFNL LFLYPANHCE GHATTLPVEL PTPYNNNSLP
SPVSPPGVSG TDYVSPITVS TPSTEDEASP VRPPHYRHMS SLSSVPTIAN VMRKESRHRQ
TYRSDTSEGS VELECPRGVE LSGSTPQEGR LATTREVDEL EGLGIKALP
//
