ID Q4WM34_ASPFU Unreviewed; 529 AA.
AC Q4WM34;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 24-JAN-2024, entry version 77.
DE SubName: Full=Peroxisomal AMP binding enzyme, putative {ECO:0000313|EMBL:EAL88980.1};
GN ORFNames=AFUA_6G11340 {ECO:0000313|EMBL:EAL88980.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL88980.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL88980.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL88980.1}.
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DR EMBL; AAHF01000006; EAL88980.1; -; Genomic_DNA.
DR RefSeq; XP_751018.1; XM_745925.1.
DR AlphaFoldDB; Q4WM34; -.
DR STRING; 330879.Q4WM34; -.
DR EnsemblFungi; EAL88980; EAL88980; AFUA_6G11340.
DR GeneID; 3508323; -.
DR KEGG; afm:AFUA_6G11340; -.
DR eggNOG; KOG1176; Eukaryota.
DR HOGENOM; CLU_000022_59_11_1; -.
DR InParanoid; Q4WM34; -.
DR OMA; IYEYYGM; -.
DR OrthoDB; 5473537at2759; -.
DR Proteomes; UP000002530; Chromosome 6.
DR GO; GO:0031956; F:medium-chain fatty acid-CoA ligase activity; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR CDD; cd05941; MCS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF15; AMP BINDING ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11340)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT DOMAIN 18..386
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 438..514
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 529 AA; 58607 MW; 31EEDBAF50F5621B CRC64;
MADSIPSLPL FLEAQKVSQH NAGKVAVIDA AKGEQFSYTQ LLVDTAELKK TILEDLGLKD
LEERRIAFLV PNGYDYVVIQ WAIWAAGGVC VPLCTTHPVK ELLYTIEDSD PSLVILHPAF
DKVREPLRES VAKDVPFMNF QSFHAKKDLS SKSLPTFSPV SFLDRRALMI YTSGTTSKPK
GCVTTHKNIT FQARCLIEAW KYSPSDHLIH VLPLHHVHGI INGLTSSFLS GATVEMHPKF
DPQVIWNRWQ DQDSSTMFMA VPTIYSRLID YFEANIRGTD KEAAARSGAK SLRLVVSGSA
ALPTPIKTKF AAITGQILLE RYGMTEIGMA LSCGLDVDKR IDGSVGWPLP GVQVRLVDKE
TGAIIETANE DGMIEIKGEN VFLEYWRQPD ATAREFTADG WFKTGDVARR DGSGAYFIQG
RASVDLIKSG GYKISALEVE RKMLGLDTIE EVAVVGLADE EWGQRVAAVV KQRPGTEPLD
LLGLRAQLKQ EMAPYKIPTV LKVVDCIERN AMGKVNKKII VQKYWPDKA
//
