ID Q4WU32_ASPFU Unreviewed; 622 AA.
AC Q4WU32;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 124.
DE SubName: Full=Ribosome biogenesis ABC transporter Arb1, putative {ECO:0000313|EMBL:EAL91894.1};
DE EC=3.6.3.- {ECO:0000313|EMBL:EAL91894.1};
GN ORFNames=AFUA_5G07020 {ECO:0000313|EMBL:EAL91894.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL91894.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL91894.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL91894.1}.
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DR EMBL; AAHF01000003; EAL91894.1; -; Genomic_DNA.
DR RefSeq; XP_753932.1; XM_748839.1.
DR AlphaFoldDB; Q4WU32; -.
DR STRING; 330879.Q4WU32; -.
DR EnsemblFungi; EAL91894; EAL91894; AFUA_5G07020.
DR GeneID; 3511058; -.
DR KEGG; afm:AFUA_5G07020; -.
DR VEuPathDB; FungiDB:Afu5g07020; -.
DR eggNOG; KOG0927; Eukaryota.
DR HOGENOM; CLU_000604_36_6_1; -.
DR InParanoid; Q4WU32; -.
DR OMA; DWMGQWT; -.
DR OrthoDB; 25181at2759; -.
DR Proteomes; UP000002530; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblFungi.
DR GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:EnsemblFungi.
DR GO; GO:0006515; P:protein quality control for misfolded or incompletely synthesized proteins; IEA:EnsemblFungi.
DR GO; GO:0000056; P:ribosomal small subunit export from nucleus; IEA:EnsemblFungi.
DR CDD; cd03221; ABCF_EF-3; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR032781; ABC_tran_Xtn.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19211:SF15; ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2; 1.
DR PANTHER; PTHR19211; ATP-BINDING TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF12848; ABC_tran_Xtn; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:EAL91894.1};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 90..331
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 401..620
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 160..187
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 11..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 622 AA; 69747 MW; C3E2A353092B5D8A CRC64;
MVSASKAARL AKRAAEGDKK KTAKSKKDVK GDESPLVDAD GEPRPTEDQP ATTEEKMKEV
EKLTAQMDKH GLSDRVTTGV LSSMASSRDV KITSASLVFH GKVLITDSTL ELNFGRRYGL
LGENGCGKST LLKAIATREY PIPEHIDIYL LNEGAPPSDL GALEWVVTEA QNQLERMEKQ
AEEILEKDGP ESPILEDLYD RMDKMDPSTF HTRASLILIG LGFNKQTIHK KTKDMSGGWR
MRVALAKALF VKPSLLLLDD PTAHLDLEAC VWLEEYLKKW ERTLVLVSHS QDFLNGVCTN
MIDMRMKQLL YYGGNYDSYH KTRSEQETNQ MKAYHKQQEE IAHIKKFIAS AGTYANLVRQ
AKSRQKILDK MEAEGFIQPV IPDRVFSFRF ADVEKLPPPV LSFDDVSFSY SGSWDDTLYE
HLDFGVDMDS RTALVGPNGV GKSTLLRLMT GKLQPIAGRV SRHTHLKLGM YSQHSAEQLD
LTKSALDFVR DKFPEKSQDY QYWRQQLGRY GLSGESQTAL MGTLSEGQKS RIVFALLAIE
CPNMILLDEP TNGLDIPTID SLADAINAFS GGVVVVSHDF RLLDKIAKDI MVCENKTIRR
WDGTIGEYKD HLRKKMVSEG AV
//
