ID Q4WXA6_ASPFU Unreviewed; 1429 AA.
AC Q4WXA6;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 24-JAN-2024, entry version 105.
DE SubName: Full=Translation repressor/antiviral protein Ski3, putative {ECO:0000313|EMBL:EAL92697.1};
GN ORFNames=AFUA_3G08810 {ECO:0000313|EMBL:EAL92697.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL92697.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL92697.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL92697.1}.
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DR EMBL; AAHF01000002; EAL92697.1; -; Genomic_DNA.
DR RefSeq; XP_754735.1; XM_749642.1.
DR STRING; 330879.Q4WXA6; -.
DR EnsemblFungi; EAL92697; EAL92697; AFUA_3G08810.
DR GeneID; 3512088; -.
DR KEGG; afm:AFUA_3G08810; -.
DR VEuPathDB; FungiDB:Afu3g08810; -.
DR eggNOG; KOG1127; Eukaryota.
DR HOGENOM; CLU_001688_2_0_1; -.
DR InParanoid; Q4WXA6; -.
DR OMA; CQWELDP; -.
DR OrthoDB; 3076611at2759; -.
DR Proteomes; UP000002530; Chromosome 3.
DR GO; GO:0055087; C:Ski complex; IBA:GO_Central.
DR GO; GO:0034427; P:nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR039226; Ski3/TTC37.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR040962; TPR_22.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR15704; SUPERKILLER 3 PROTEIN-RELATED; 1.
DR PANTHER; PTHR15704:SF7; TETRATRICOPEPTIDE REPEAT PROTEIN 37; 1.
DR Pfam; PF13432; TPR_16; 2.
DR Pfam; PF14559; TPR_19; 1.
DR Pfam; PF18833; TPR_22; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 459..492
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 655..688
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 731..764
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 991..1024
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 330..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1429 AA; 160701 MW; 7CAFD06179DF251C CRC64;
MAGQRSELSS MSTKSALKAA RIALDSRDFE DAAEKAKVVV KQEPQNYHAN VFLGLALDKL
NKNEESERAY RAATRAKSDD KTAWQGLINL YEKQGGFKLD AYHEAALRLG QIFAEVDDKH
RCQDVVDKYI KFAKKQGTRS QYKKALELHL PTSPLYVYLE GRIPHPSHTY LRLIEMAESE
EKEFINREIG ERRTRLGARI DHVTMEVKRE AFKRGELEQL YRGIVDWTHD DQVRRTYEER
LLQRAYDILI VLPPAEKAEK RAEVLQAARD MVIIKHPFEL AWKIVLEWQD IQSFSEWDLN
FLKDFIEFFP EDGLTKILKG FLASDLSPFS KETKETKEPT PTEEETENGN GDNHELAVQD
RLLMMVEGLE SSRSSIVANR IMGELYLSLE EYDSVVDVAR KGLSNITDLA RLTGISLVNT
TDCLKTLLAN SLIYYQIPRH HPEAKEIFED VLQRKPTFTA CLLGIGLILK VDEDYAEAVN
FLERALERDP SNLKIRGELS WCKALNGDLE TGLHGLQDVL AELQDMESPN REFKSEILYR
IGYCQWELDP SPTARKDRSG AYASFLGSIQ SNINFAPAYT SLGIYYADYK KDKTRARRCF
HKAFELSASE IEAAERLART FADQKEWDLV EAVAQRVVDS GKAKPSPGSK RRGYSWPYAA
LGTVQMNKQQ YAQSIVSFQA ALRISPGDYH SWVGLGESYH HSGRYIASAK AFDHAQQLES
ALSSDEREHI WFARYMLANV KRELGEFKDA ISRYEDVLKF RPNELGVTIA LLQTLIESAW
KSLESGLYND SVELARNAIV VAASLAKERV DIFNLWKAVG DACAMFTYVK GKASKFPLQE
VKALLTTQVE PSAFDMFAEI DELGQGCLSL LDEDSDTISP SDKCIYASIL AYKRAIYVSA
QDVHARAVAW YNLGWAEYRA QRCVQVHSGT KGKKPARRFL KTAMRCFKRA IELEAGNSEF
WNALGVATTS MSPKVAQHAF VRSLHLNERS AQVWTNLGTL YLIHNDIQLA NEAFTRAQST
DPDYSLAWVG QGFLALLFGD PLEARGLFEH AFDISNSSST LPRRQYTLTL FDRLLSDSSA
SNEISQLIQP LFALLQLSSQ DPSNLQFMHL TALMAERIGE LSDAETSLHV VCSGVEAEYE
VSESSSSLSR YAQSNADMAR VLLARQEFEQ AVEKAEVALT LSGEEDAEKF DPEANRKLRL
SAHLTAGLAH YYLKSMDNAI DMFRDALQEA DNAPEVVCLL AQVLWAKGGD EERTVARQQL
FDCVEEHPDH VGAVSLLGAI ALLDDDKDVI EAVASDLQNM IMRDDIDIHD RTRLTKLLTA
ISTLGLTEDS QIPEDVRRLG EATAAVMRSP GQPQGWQELA AASQELYPAE MAVDRALRSV
PPRSNLDAVD LCEAYAQTGK AGDAIKAIMV APWKQCGWEE LKYAVSELV
//
