ID Q50320_MYCPC Unreviewed; 361 AA.
AC Q50320; Q73U41;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 133.
DE SubName: Full=34KDa protein {ECO:0000313|EMBL:CAA80638.1};
DE SubName: Full=Serine protease {ECO:0000313|EMBL:ANH30108.1, ECO:0000313|EMBL:WAI54467.1};
GN ORFNames=A0V42_18125 {ECO:0000313|EMBL:ANH30108.1}, EC390_06755
GN {ECO:0000313|EMBL:AYQ67975.1}, OUZ54_22550
GN {ECO:0000313|EMBL:WAI54467.1};
OS Mycobacterium paratuberculosis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=1770 {ECO:0000313|EMBL:CAA80638.1};
RN [1] {ECO:0000313|EMBL:CAA80638.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JD88/107 {ECO:0000313|EMBL:CAA80638.1};
RX PubMed=7921248;
RA Cameron R.M., Stevenson K., Inglis N.F., Klausen J., Sharp J.M.;
RT "Identification and characterisation of a putative serine protease
RT expressed in vivo by Mycobacterium avium subsp paratuberculosis.";
RL Microbiology 140:1977-1982(1994).
RN [2] {ECO:0000313|EMBL:ANH30108.1, ECO:0000313|Proteomes:UP000077548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAP/TANUVAS/TN/India/2008 {ECO:0000313|EMBL:ANH30108.1,
RC ECO:0000313|Proteomes:UP000077548};
RA Bhuvaneswari S., Vijayarani K., Tirumurugaan K., Shiek A.S.S.J.,
RA Alexandar V., Kumanan K.;
RT "Complete genome analysis of an Indian isolate of Mycobacterium avium
RT subsp. paratuberculosis from cattle.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AYQ67975.1, ECO:0000313|Proteomes:UP000267467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAPK_CN9/15 {ECO:0000313|EMBL:AYQ67975.1,
RC ECO:0000313|Proteomes:UP000267467};
RA Yoo H.S., Kim D., Park H.-T., Lee G.M.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:WAI54467.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LN20 {ECO:0000313|EMBL:WAI54467.1};
RA Behr M.A., Conde C., Mcintosh F.A., Cochard T., Bannantine J.P., Biet F.;
RT "Complete genome assembly of Mycobacterium avium subspecies
RT paratuberculosis strain LN20.";
RL Submitted (NOV-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
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DR EMBL; CP015495; ANH30108.1; -; Genomic_DNA.
DR EMBL; CP033427; AYQ67975.1; -; Genomic_DNA.
DR EMBL; Z23092; CAA80638.1; -; Genomic_DNA.
DR EMBL; CP113485; WAI54467.1; -; Genomic_DNA.
DR PIR; S47170; S47170.
DR RefSeq; WP_003874244.1; NZ_LKUT01000283.1.
DR SMR; Q50320; -.
DR KEGG; mavi:RC58_01175; -.
DR KEGG; mavu:RE97_01185; -.
DR PATRIC; fig|1770.26.peg.4084; -.
DR OMA; NFRMGPG; -.
DR Proteomes; UP000077548; Chromosome.
DR Proteomes; UP000267467; Chromosome.
DR Proteomes; UP001164279; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR43343; PEPTIDASE S12; 1.
DR PANTHER; PTHR43343:SF3; PROTEASE DO-LIKE 8, CHLOROPLASTIC; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ANH30108.1};
KW Protease {ECO:0000313|EMBL:ANH30108.1}.
FT DOMAIN 271..322
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 361 AA; 35709 MW; 30FEF78FD6F3C411 CRC64;
MSKSHHHRSV WWSWLVGVLT VVGLGLGLGS GVGLAPASAA PSGLALDRFA DRPLAPIDPS
AMVGQVGPQV VNIDTKFGYN NAVGAGTGIV IDPNGVVLTN NHVISGATEI SAFDVGNGQT
YAVDVVGYDR TQDIAVLQLR GAAGLPTATI GGEATVGEPI VALGNVGGQG GTPNAVAGKV
VALNQSVSAT DTLTGAQENL GGLIQADAPI KPGDSGGPMV NSAGQVIGVD TAATDSYKMS
GGQGFAIPIG RAMAVANQIR SGAGSNTVHI GPTAFLGLGV TDNNGNGARV QRVVNTGPAA
AAGIAPGDVI TGVDTVPING ATSMTEVLVP HHPGDTIAVH FRSVDGGERT ANITLAEGPP
A
//
