ID Q504A2_DANRE Unreviewed; 306 AA.
AC Q504A2; A0A8M1N5U1;
DT 07-JUN-2005, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2005, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Zgc:109986 {ECO:0000313|EMBL:AAH95107.1, ECO:0000313|Ensembl:ENSDARP00000134216};
GN ORFNames=zgc:109986 {ECO:0000313|EMBL:AAH95107.1,
GN ECO:0000313|Ensembl:ENSDARP00000134216,
GN ECO:0000313|RefSeq:NP_001018381.1,
GN ECO:0000313|ZFIN:ZDB-GENE-050522-136};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH95107.1};
RN [1] {ECO:0000313|RefSeq:NP_001018381.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12477932; DOI=10.1073/pnas.242603899;
RG Mammalian Gene Collection Program Team;
RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D.,
RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F.,
RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H.,
RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K.,
RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F.,
RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S.,
RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J.,
RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J.,
RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M.,
RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G.,
RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C.,
RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I.,
RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.;
RT "Generation and initial analysis of more than 15,000 full-length human and
RT mouse cDNA sequences.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002).
RN [2] {ECO:0000313|EMBL:AAH95107.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye {ECO:0000313|EMBL:AAH95107.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSDARP00000134216, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000134216};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [4] {ECO:0000313|Ensembl:ENSDARP00000134216}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000134216};
RG Ensembl;
RL Submitted (NOV-2015) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001018381.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=28329862;
RA Schuttler A., Reiche K., Altenburger R., Busch W.;
RT "The Transcriptome of the Zebrafish Embryo After Chemical Exposure: A Meta-
RT Analysis.";
RL Toxicol. Sci. 157:291-304(2017).
RN [6] {ECO:0000313|RefSeq:NP_001018381.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BX088587; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC095107; AAH95107.1; -; mRNA.
DR RefSeq; NP_001018381.1; NM_001020545.1.
DR STRING; 7955.ENSDARP00000134216; -.
DR PaxDb; 7955-ENSDARP00000026202; -.
DR Ensembl; ENSDART00000166081.2; ENSDARP00000134216.1; ENSDARG00000102608.2.
DR GeneID; 553566; -.
DR KEGG; dre:553566; -.
DR AGR; ZFIN:ZDB-GENE-050522-136; -.
DR ZFIN; ZDB-GENE-050522-136; zgc:109986.
DR eggNOG; ENOG502QTI1; Eukaryota.
DR HOGENOM; CLU_057934_0_0_1; -.
DR OMA; MEPSEQV; -.
DR OrthoDB; 5476411at2759; -.
DR TreeFam; TF313812; -.
DR Proteomes; UP000000437; Chromosome 17.
DR Bgee; ENSDARG00000102608; Expressed in granulocyte and 19 other cell types or tissues.
DR GO; GO:0008168; F:methyltransferase activity; IBA:GO_Central.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR026669; Arsenite_MeTrfase-like.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43675; ARSENITE METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43675:SF1; RIKEN CDNA 2700097O09 GENE; 1.
DR Pfam; PF13847; Methyltransf_31; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT DOMAIN 145..259
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13847"
SQ SEQUENCE 306 AA; 34691 MW; F5676FCB6A466FC9 CRC64;
MNFNDAKNEI LQVLSKTERQ HLPKLLEWIK TSDDLDDILV DNQSVILHSI AEDLRACLPM
EAMAPSETLA MQKTQQKAHP TVHVDAFLYD DETVDSLCEE GKMSRTYCLN CGSHRTAPLE
FISHSFSIPE LQFLFHNVLP ELTGKLVLDV GSRLGAVLFG GYLYSAASQL VGVEMSSEFV
KLQSMAVEKY GFSDRIQVIH ADIRSQIALV QKADVLIMNN VFEYFMEPRD QMQAWLYISQ
NFRKKGALLV TVPSIQEALG LLQDAAFLET LSLSQWIEEI PVDYSVYLKN DTDPDSLKQI
HLYRVL
//
