ID Q52L43_XENLA Unreviewed; 231 AA.
AC Q52L43;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 75.
DE SubName: Full=LOC443711 protein {ECO:0000313|EMBL:AAH94075.1};
DE Flags: Fragment;
GN Name=LOC443711 {ECO:0000313|EMBL:AAH94075.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH94075.1};
RN [1] {ECO:0000313|EMBL:AAH94075.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye {ECO:0000313|EMBL:AAH94075.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the distal-less homeobox family.
CC {ECO:0000256|ARBA:ARBA00007916}.
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DR EMBL; BC094075; AAH94075.1; -; mRNA.
DR AlphaFoldDB; Q52L43; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR000047; HTH_motif.
DR PANTHER; PTHR24327; HOMEOBOX PROTEIN; 1.
DR PANTHER; PTHR24327:SF26; HOMEOBOX PROTEIN DLX-6; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 103..163
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 105..164
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 15..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAH94075.1"
SQ SEQUENCE 231 AA; 25920 MW; 69C5A4FC7DEB573F CRC64;
HSQQSSPVMA AGHYPLHCLH SGSHPHHHPH HQHDTNYSGS NSYSRSLAAY PYMSHSQHSP
YLQTYNSNSS SSTTTQNRAE EPADQQKTTV IENGEIRFNG KGKKIRKPRT IYSSLQLQAL
NHRFQQTQYL ALPERAELAA SLGLTQTQVK IWFQNKRSKY KKLLKQGSNP LESDPLPGTA
ALSPRSPAIP PVWDVSATAK GVSMAPNSYM PGYSHWYSSP HQDTMQRSQM M
//
