ID Q54N55_DICDI Unreviewed; 374 AA.
AC Q54N55;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=Transcription initiation factor TFIID subunit 8 {ECO:0000256|ARBA:ARBA00017307};
GN ORFNames=DDB_G0285493 {ECO:0000313|EMBL:EAL64584.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL64584.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL64584.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL64584.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF8 family.
CC {ECO:0000256|ARBA:ARBA00008767}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL64584.1}.
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DR EMBL; AAFI02000079; EAL64584.1; -; Genomic_DNA.
DR RefSeq; XP_638088.1; XM_632996.1.
DR AlphaFoldDB; Q54N55; -.
DR SMR; Q54N55; -.
DR STRING; 44689.Q54N55; -.
DR PaxDb; 44689-DDB0186530; -.
DR GeneID; 8625134; -.
DR KEGG; ddi:DDB_G0285493; -.
DR dictyBase; DDB_G0285493; -.
DR eggNOG; KOG2389; Eukaryota.
DR HOGENOM; CLU_740647_0_0_1; -.
DR InParanoid; Q54N55; -.
DR OMA; SCRTDSN; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR CDD; cd08049; TAF8; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR006565; BTP.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037818; TAF8.
DR InterPro; IPR019473; TFIID_su8_C.
DR PANTHER; PTHR46338; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8; 1.
DR PANTHER; PTHR46338:SF1; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8; 1.
DR Pfam; PF07524; Bromo_TP; 1.
DR Pfam; PF10406; TAF8_C; 1.
DR SMART; SM00576; BTP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..79
FT /note="Bromodomain associated"
FT /evidence="ECO:0000259|SMART:SM00576"
FT REGION 190..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 43126 MW; 6FE857F5018C9F7C CRC64;
MCDNFARVLC KIVVAQVAKN LGFPSISQIA TDFLADVIQL DIQDIGIRAH EYSELSCRTD
SNFFDVKQAF EDMAINIHEL QQFLLQSDEI PFAQVVPPFP LQGSVEQPSK PSPYKTEEQE
FPLHIPSFLP SFPEKHTFSK TPLYGEVVTD PYKIKKTKNK QKRQIENSLI KLTDITTTKI
PNYDMIKQQQ YSKKEEASGV NNNNNNNSKQ NNKIYNKNNE GRNNHNENNN KKDDDKMNLD
SNNNDDSNSN EFNKNNYNNN NNNNTSGNKD GENNNNNNNN NNNNNNKNNK QEINRDIIPP
TPLESVSNTF YQKLEEEDLK KHHDEAPRRS LLSEEDQERA KKRVKCERIL SLVHESSHST
INEDDKDKDI IEHD
//
