ID Q54PQ7_DICDI Unreviewed; 1089 AA.
AC Q54PQ7;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 112.
DE SubName: Full=Peptidase C19 family protein {ECO:0000313|EMBL:EAL65239.1};
GN ORFNames=DDB_G0284381 {ECO:0000313|EMBL:EAL65239.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL65239.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL65239.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL65239.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL65239.1}.
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DR EMBL; AAFI02000064; EAL65239.1; -; Genomic_DNA.
DR RefSeq; XP_638597.1; XM_633505.1.
DR AlphaFoldDB; Q54PQ7; -.
DR SMR; Q54PQ7; -.
DR STRING; 44689.Q54PQ7; -.
DR PaxDb; 44689-DDB0237697; -.
DR GeneID; 8624568; -.
DR KEGG; ddi:DDB_G0284381; -.
DR dictyBase; DDB_G0284381; -.
DR eggNOG; KOG1870; Eukaryota.
DR HOGENOM; CLU_001060_7_1_1; -.
DR InParanoid; Q54PQ7; -.
DR OMA; WERVGHR; -.
DR PhylomeDB; Q54PQ7; -.
DR Reactome; R-DDI-5689880; Ub-specific processing proteases.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:UniProtKB-EC.
DR CDD; cd02674; Peptidase_C19R; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR Gene3D; 3.30.2230.10; DUSP-like; 1.
DR InterPro; IPR035927; DUSP-like_sf.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR006615; Pept_C19_DUSP.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR21646:SF21; UBIQUITINYL HYDROLASE 1; 1.
DR Pfam; PF06337; DUSP; 1.
DR Pfam; PF00443; UCH; 1.
DR SMART; SM00695; DUSP; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF143791; DUSP-like; 1.
DR PROSITE; PS51283; DUSP; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002195}.
FT DOMAIN 1..161
FT /note="DUSP"
FT /evidence="ECO:0000259|PROSITE:PS51283"
FT DOMAIN 403..1070
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 47..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1089 AA; 123545 MW; A08EA0919A76DDEB CRC64;
MRNEQLEQKK LIKENWSQEL VSGEVVNIIS ARWLKLWKNY VKYDDNTTLN SSNTTPLNCS
TTTSTTTTTT TTTTATTNNK SVEDNNNSSA NNNNNNSIQF DSAKPESIDN REIIEGNDSE
GEPIVSKRVT EKEDYEIIPN RVWKLLVSWY QGGPEIKRKV VELGVRNELY VEVRPLLVGV
KYHQSLISEL SKLPPSSTSN NSTKEFLFQK SLKSSLSELR EYIGKVENID PMKLVFYNNN
NSNSGSIKIK PIKRDYLTLE DLKFENSSQL ILHFQPNNNC HSSSNSSSSA SSSDQSSSHH
NPKLMNKISK KIGNIFKKKT HPGRSYSDPS YYQNNGSSNN NNSNGNGGNN GNQSGGASTT
NGGMNIRDNS STSSTSSSNS NENSPTFEQN GSTKELISNG KVCGLSNLGN TCFMNSSIQC
LAHTGPLVEY FLSGRYLGDI NKTNPLGMKG QIADIYGKLM KDMWSGSSCV APKHLKWIIG
KYAPQFSGIS QQDSQELLSF LLDGLHEDLN KVIKKPYQEE KDEPKEPRED IVVANEQWDN
HIKRNQSIIV NLFQGQYKST LVCAKCSKVS ITFDPYMFVT LPIPVPTERL FDVLLFRRKP
QMGSEALGPD PNGIYCLNNA MSPIKYCLKL PKREDVETLR VELSKIVGIE SSCIALAETF
KNRIYTFLND QKNLISIKDK DVTIAYELPH AGDDISRIHV MHRKKNDLTL LPYVLLLNYS
ETTCKDLYRM VWERVGHRVK KGWKSALKQK LSKENIQLPN NNSNEENENI NNTNNNNTNN
NTNNNTNNQQ QQQQDILSNF EKDSHISTND EMFEEDDTSS VTDDEMFESI YPFILKTTNG
YGNHCDRCPN GCTGCPVECN DKPLHSLYKN PKYWREGCNN LTIDWRPEIL KYIDFTEHDD
PNSPFTVQDK SIQLKTEFRN EITLNDCLQL YTKSEKLGTN DTWYCPQCKA HIEGSMKKLE
LWSAPKILVV HLKRFHYVHG HRHEKINAFV DFPLDNLDIS QWVLNKSNPP PIYQLYAVSN
HMGGMGSGHY TSCIKNNKDQ WYLISDSSYH AIDKSKVKTS DAYVLFYELK QQPPQQPQSS
QNASIHPIN
//
