ID Q54R91_DICDI Unreviewed; 699 AA.
AC Q54R91;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 109.
DE SubName: Full=Tetratricopeptide-like helical domain-containing protein {ECO:0000313|EMBL:EAL65794.1};
GN Name=prpf39 {ECO:0000313|EMBL:EAL65794.1};
GN ORFNames=DDB_G0283307 {ECO:0000313|EMBL:EAL65794.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL65794.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL65794.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL65794.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the PRP39 family.
CC {ECO:0000256|ARBA:ARBA00038019}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL65794.1}.
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DR EMBL; AAFI02000052; EAL65794.1; -; Genomic_DNA.
DR RefSeq; XP_639156.1; XM_634064.1.
DR AlphaFoldDB; Q54R91; -.
DR SMR; Q54R91; -.
DR STRING; 44689.Q54R91; -.
DR PaxDb; 44689-DDB0233547; -.
DR GeneID; 8624026; -.
DR KEGG; ddi:DDB_G0283307; -.
DR dictyBase; DDB_G0283307; prpf39.
DR eggNOG; KOG1258; Eukaryota.
DR HOGENOM; CLU_394551_0_0_1; -.
DR InParanoid; Q54R91; -.
DR OMA; XTFEHAV; -.
DR PhylomeDB; Q54R91; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0000243; C:commitment complex; IBA:GO_Central.
DR GO; GO:0005685; C:U1 snRNP; IBA:GO_Central.
DR GO; GO:0071004; C:U2-type prespliceosome; IBA:GO_Central.
DR GO; GO:0000395; P:mRNA 5'-splice site recognition; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR17204; PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; 1.
DR PANTHER; PTHR17204:SF5; PRE-MRNA-PROCESSING FACTOR 39; 1.
DR SMART; SM00386; HAT; 7.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002195}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..667
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..691
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 82461 MW; 97015532698FC70E CRC64;
MTEVTTTPPT TSTPTTSPQN LSEEDKLWKI VQTNPLAFNQ WTFLIGVIEK TNDIEKIRKV
YSEFLNEFPL CFLYWKRFAD HEYAHNNTTQ SIEIFEKAVS SIPHSVDIWL NYCTHLIDKS
YPVDEIRSVF KRGINIIGTD YQSGKFWEKY IEFEMGQENN ELASIFNSIL KTPLENLQIF
NEKFKDNIDR IKINDMLTEE ERKEYTGYDA ETKQMVLQNR EKWYHETLEK ISKRSNFESI
VNKRFFFHIQ PIDEMTLSVW RSYFNYMESD PSVTQEEVIK LFERCLVPCC YYSEFWLKYI
KFLQESYVGD NKNELIESIF ERATKIFLKK RADIHLEYSL FVESTLGNIE KAFSILENIH
SLLPTHLEVI LRLVSFKRRN HSIQQANQFF KKVLTSLQSD SKTYPFLSIN YISFLLSNKQ
SLQGEKEGEE EADKIVDVFE TSREVLKKSI SLYPDSKLLW LYFINFEINN LLFIISGSGS
SEKRIEQIER IKKVYNIALC LDKNKIKNNG KENKEENKEE NKENTNNEEK EKEKDDEEKD
DEEKDGNEIL VCKLNDDEKL NIWNDYLEFN LQYDNDIKGY KELKNKFESL YPDGKPESKK
RSLTDMNLQS SSSSSSSTTN GIINNGNNDG PLNKRVAYSV PPTSNNNGVI QNNSYIYQQQ
QAQPQHHHQQ QQHHHQQHIQ QQQQHHQQQH QGFYGGYGY
//
