ID WDR55_DICDI Reviewed; 408 AA.
AC Q54SA5;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 98.
DE RecName: Full=WD repeat-containing protein 55 homolog;
GN Name=wdr55; ORFNames=DDB_G0282573;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR EMBL; AAFI02000047; EAL66146.1; -; Genomic_DNA.
DR RefSeq; XP_640134.1; XM_635042.1.
DR AlphaFoldDB; Q54SA5; -.
DR SMR; Q54SA5; -.
DR STRING; 44689.Q54SA5; -.
DR PaxDb; 44689-DDB0304577; -.
DR EnsemblProtists; EAL66146; EAL66146; DDB_G0282573.
DR GeneID; 8623671; -.
DR KEGG; ddi:DDB_G0282573; -.
DR dictyBase; DDB_G0282573; -.
DR eggNOG; KOG2444; Eukaryota.
DR HOGENOM; CLU_035848_2_1_1; -.
DR InParanoid; Q54SA5; -.
DR OMA; MFENLCT; -.
DR PhylomeDB; Q54SA5; -.
DR PRO; PR:Q54SA5; -.
DR Proteomes; UP000002195; Chromosome 3.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44019; WD REPEAT-CONTAINING PROTEIN 55; 1.
DR PANTHER; PTHR44019:SF20; WD REPEAT-CONTAINING PROTEIN 55; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..408
FT /note="WD repeat-containing protein 55 homolog"
FT /id="PRO_0000373969"
FT REPEAT 17..56
FT /note="WD 1"
FT REPEAT 61..100
FT /note="WD 2"
FT REPEAT 104..141
FT /note="WD 3"
FT REPEAT 144..183
FT /note="WD 4"
FT REPEAT 186..224
FT /note="WD 5"
FT REPEAT 227..265
FT /note="WD 6"
FT REPEAT 268..308
FT /note="WD 7"
FT REGION 308..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..341
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..371
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..408
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 408 AA; 46002 MW; 767648BC732D0D28 CRC64;
MDTSSEGDHE LAPNDISFNT IPFSLNFHPT EDLLVVSDAE GRLKLFKYSL DENEVKLSLR
PHQSGCRQAN FSSDGKYIFT ASSDCSMKVI DINTGSILYT REEAHDYPIN CLVSKEFMVF
TGDDEGTIKV WDMRQQNIVC EFQEHGDFIS DITTIDDRHI AATSGDGGVS IYNFVRKSMD
DISEKSDNEL LSCLSLDNGQ KLVCGSQDGS ILIYDRNNLE NVKKFAGHPQ SVDALVKVNN
NTFFSGSSDG IIRFIGLRPK KLLGVVGEHS TFPIERMAIS RDNRYLGSIS HDFSLKFWNV
ASFYEEDESE DADSANANAN EIENDDDDDD DDDEIEDIEN ATKVDDDSGS EMGDDDDDDD
DEEQEEEEES SSDEDIKRKK PQQNPIKAQQ IEKQKQKQNQ KRSFFKDL
//
