ID Q54XE1_DICDI Unreviewed; 998 AA.
AC Q54XE1;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 75.
DE RecName: Full=Transglutaminase-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DDB_G0279021 {ECO:0000313|EMBL:EAL67932.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL67932.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL67932.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL67932.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL67932.1}.
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DR EMBL; AAFI02000026; EAL67932.1; -; Genomic_DNA.
DR RefSeq; XP_641916.1; XM_636824.1.
DR AlphaFoldDB; Q54XE1; -.
DR STRING; 44689.Q54XE1; -.
DR PaxDb; 44689-DDB0215303; -.
DR GeneID; 8621834; -.
DR KEGG; ddi:DDB_G0279021; -.
DR dictyBase; DDB_G0279021; -.
DR eggNOG; ENOG502RECZ; Eukaryota.
DR HOGENOM; CLU_300255_0_0_1; -.
DR InParanoid; Q54XE1; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.10.620.30; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR006642; Rad18_UBZ4.
DR InterPro; IPR002931; Transglutaminase-like.
DR PANTHER; PTHR37002; AGAP007005-PA; 1.
DR PANTHER; PTHR37002:SF8; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01841; Transglut_core; 1.
DR SMART; SM00460; TGc; 1.
DR SMART; SM00734; ZnF_Rad18; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 391..414
FT /note="UBZ4-type"
FT /evidence="ECO:0000259|SMART:SM00734"
FT DOMAIN 868..930
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT REGION 13..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 998 AA; 116201 MW; 6940A8642F6040AE CRC64;
MIRFLLNSLI DEEDNNNNSN SNNNNNNKIK KEKEDNETFE LVKNEFLKLI KSIEETKESL
YQYVNNFQDV FLNQTNIYNT IKNNFRDDHP LYHYSNQVLV NISNVFKNRK TNFEKNIESI
LNYLDKANYL KLKLDNLNQF HTNIINNNNN NNQTNLNKKI IEEYLDLKVL LFSELKSFFD
ERVTSYDLPL INIQMIFNIV YDEIGMVFKN SLDFLKQTNT INITTLKTVL NRPSGFYSTS
KINNNNYNNN DFILPPHLND YSSYQEYQKK LNQPPQPQPP QHINQQQQQQ QPNQTLNQQN
HHETQLRPQR QPQNQPNNFT MYPFELYQQP QPQQQQQQQQ QQQQQQQQQQ QQQQQRQQPY
PRRTPVFPRP TPTMPTTTSP QSSQLPIQEI LVSCPICSNQ YREIEINEHI DIHLNEQSQI
NNNNNNNNNN NIINGNGNNN YQGSYDLIEP MDTPTTTTTT TTTTTASHII EPLSYDQQNS
NSESKPTKRK NKKNLLKKLV KFLSRSKKSK PKKSKRIKKN TNTPNIIDIT SVDTSNNIVD
NNKPIEFDKT PINFNDNNNN NNNNNNNNNN NNNNNNNFPG SSNNYLNASN STRPQSPIYN
NNNNNNNNNN NNNNNNNNNN NNNNNNRSYQ LLKEKENKIK VNLVDKLVRF EFKMPTIFEP
SLENYLFDYE AHKNMWDKKP LKLVKTHKHT IRYVLTIQVS KISGIVYSST YFINKPLNLS
SQFVRSSSFS AFSVDGKQML CDSKLIKTNT NPIYKLFYNK PISNYLLKQE IEVDLFSVKL
TQIDIGDGDT TDVVVVEPLS IQERDFYLIQ TYPPTEEFKQ FIAFNKLSPQ ITSNGEMESL
LCFAYRVTLY IRKIEYLKEA GDQEPMETIR SGKANCTSFS ILFSSIMRFN GIPCRTIIGR
NAGAFRSEMG HAKNEFYHPS YGFIPVDCSL KDNSVYNTHC FADHSGDLLV LTVENITCKE
FNQNEKLSLI LPATLHSYNQ ARPPVFTPFT DNFSILNC
//
