ID Q55BE9_DICDI Unreviewed; 414 AA.
AC Q55BE9;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=GP-PDE domain-containing protein {ECO:0000259|PROSITE:PS51704};
GN ORFNames=DDB_G0271374 {ECO:0000313|EMBL:EAL71817.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL71817.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL71817.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL71817.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=12097910; DOI=10.1038/nature00847;
RG Dictyostelium Genome Sequencing Consortium;
RA Glockner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2] {ECO:0000313|EMBL:EAL71817.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL71817.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL71817.1}.
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DR EMBL; AAFI02000006; EAL71817.1; -; Genomic_DNA.
DR RefSeq; XP_645663.1; XM_640571.1.
DR AlphaFoldDB; Q55BE9; -.
DR SMR; Q55BE9; -.
DR STRING; 44689.Q55BE9; -.
DR PaxDb; 44689-DDB0216796; -.
DR GeneID; 8617855; -.
DR KEGG; ddi:DDB_G0271374; -.
DR dictyBase; DDB_G0271374; -.
DR eggNOG; KOG2258; Eukaryota.
DR HOGENOM; CLU_030006_3_5_1; -.
DR InParanoid; Q55BE9; -.
DR OMA; DIVWITI; -.
DR PhylomeDB; Q55BE9; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08561; GDPD_cytoplasmic_ScUgpQ2_like; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR43805; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR PANTHER; PTHR43805:SF1; GP-PDE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 55..327
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 414 AA; 47627 MW; 5A4F18279DC75390 CRC64;
MKDNKTKLII YFFIAIISGY IYYSNQQLNK QNIVKQVIYE KLHTKNLIIN GEDKPIILAH
RGSRYLLPEN TILAFKTALD IGADVIETDV RKTIDGELVI FHDKSVERTT NGKGDVEELT
LKELKSLDAA YRFSADNGTT YPYRGKGIQV PTLVEMFESL PSDTQINIEI KEDDMEVAEK
LWKEIEHQME TTTRKPKSIL IGSRYCPPTQ HIRSLAKLYQ TRNNIAQLPI STSACEKDVT
KFVVLNQLFL APIYFSMYPI TGYECFQVPV ASGPIHLDTL KFIDAAHHFG KHVHFWVVNF
KDEIDHLLTL PIDGIISDRP DRVVEQFKSH NIKSKQFQIP KPLPSNTTGT YYLPLYDIDE
NHTCVTITCI LLQRSHQIVI SLIFSFLLLK LINFKNNNNN NRQVKNQNLQ KKVK
//
