ID Q55F13_DICDI Unreviewed; 660 AA.
AC Q55F13;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=TH1 family protein {ECO:0000313|EMBL:EAL72928.1};
GN ORFNames=DDB_G0268678 {ECO:0000313|EMBL:EAL72928.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL72928.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL72928.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL72928.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NELF-D family.
CC {ECO:0000256|ARBA:ARBA00005726}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL72928.1}.
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DR EMBL; AAFI02000004; EAL72928.1; -; Genomic_DNA.
DR RefSeq; XP_646857.1; XM_641765.1.
DR AlphaFoldDB; Q55F13; -.
DR SMR; Q55F13; -.
DR STRING; 44689.Q55F13; -.
DR PaxDb; 44689-DDB0232149; -.
DR GeneID; 8616540; -.
DR KEGG; ddi:DDB_G0268678; -.
DR dictyBase; DDB_G0268678; -.
DR eggNOG; ENOG502QPUE; Eukaryota.
DR HOGENOM; CLU_028060_0_0_1; -.
DR InParanoid; Q55F13; -.
DR OMA; CHSEHTY; -.
DR PhylomeDB; Q55F13; -.
DR Reactome; R-DDI-674695; RNA Polymerase II Pre-transcription Events.
DR Reactome; R-DDI-6796648; TP53 Regulates Transcription of DNA Repair Genes.
DR PRO; PR:Q55F13; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0032021; C:NELF complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0034244; P:negative regulation of transcription elongation by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR006942; TH1.
DR PANTHER; PTHR12144:SF0; NEGATIVE ELONGATION FACTOR C_D; 1.
DR PANTHER; PTHR12144; NEGATIVE ELONGATION FACTOR D; 1.
DR Pfam; PF04858; TH1; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 660 AA; 75605 MW; 766C8923F2B48152 CRC64;
MSTSPTHHQQ QQQQHQTSPT HNQHTSPTHQ QQQQQQQQQP TSPIHQQQQK QTSPTHNQPT
SPTNSSTTTT TTTTNTNTLK TPTDLIKEKC ESSLQQPDSI MSIEASSLMK EYITVGGRPQ
DVITFLSESY RGYAQMCNLL CYWLKIAGIP EEQIQTQFSN HLKEIIINKF DPKVADTIFT
SSSTPPHWLD EMIVDSQWRS LIYQLSEEHK NCLMLNFIIQ RISDSGYQNE IASLSTASTY
YRVFNKVLFD SLADLVTLDE ISFRQQLDEF KKSCCQHQHT YLYAQATIQN LIKNNPQKAY
NLKRISQELE IEATKKNKIA QRISLMMSNI SQYPLISSSI TSLLMSNTTT TGDIIKLYNE
YTKAQPPPVD FLRYPNLLEL LLSDLFCPGK VIQSVHKSKW IYLVTYSVCI NSSSSSNEKD
NNVFKDITRA IEIVHNICQS NPLGSELQSV VGTLKDHLDF PIISMGIMQW IKHNLTDTTN
LSSYNTLCVP IYLDFLRDIC LRHPLHRSVV LNILVSHFEV EAQDLESLAI LEMRKNVIDN
IVYLFSCGYV IPVLDTIESW APKIDPSLTR YFINQVLDII EPPYSQSFMD KMKSIIKIIN
PFGESTKLEP SVQSFLDQCK NQLILNNNNN NNNNNLSTKT STKRNNTEIY NNEDENEQVF
//
