ID   Q57H63_SALCH            Unreviewed;       252 AA.
AC   Q57H63;
DT   10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2005, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   SubName: Full=Catalyzes the adenylation of thisS as part of thiazole synthesis, also with ThiI it catalyses the transfer of sulfur from cysteine to the ThiS enzyme {ECO:0000313|EMBL:AAX67949.1};
GN   Name=thiF {ECO:0000313|EMBL:AAX67949.1};
GN   OrderedLocusNames=SCH_4043 {ECO:0000313|EMBL:AAX67949.1};
OS   Salmonella choleraesuis (strain SC-B67).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=321314 {ECO:0000313|EMBL:AAX67949.1, ECO:0000313|Proteomes:UP000000538};
RN   [1] {ECO:0000313|EMBL:AAX67949.1, ECO:0000313|Proteomes:UP000000538}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC-B67 {ECO:0000313|EMBL:AAX67949.1,
RC   ECO:0000313|Proteomes:UP000000538};
RX   PubMed=15781495; DOI=10.1093/nar/gki297;
RA   Chiu C.H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.Y., Wang H.S.,
RA   Lee Y.S.;
RT   "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT   invasive and resistant zoonotic pathogen.";
RL   Nucleic Acids Res. 33:1690-1698(2005).
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DR   EMBL; AE017220; AAX67949.1; -; Genomic_DNA.
DR   RefSeq; WP_000999763.1; NC_006905.1.
DR   AlphaFoldDB; Q57H63; -.
DR   KEGG; sec:SCH_4043; -.
DR   HOGENOM; CLU_013325_10_3_6; -.
DR   Proteomes; UP000000538; Chromosome.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   CDD; cd00757; ThiF_MoeB_HesA_family; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR10953:SF240; SULFUR CARRIER PROTEIN THIS ADENYLYLTRANSFERASE; 1.
DR   PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   4: Predicted;
FT   DOMAIN          9..242
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   252 AA;  26904 MW;  879E730A97A30B5E CRC64;
     MNDRDFMRYS RQILLGDIAI EGQQKLLASH VLIVGLGGLG SPAALYLAGA GIGTLTLADD
     DDVHLSNLQR QILFTTDDIA HPKAQAAKLR LAQLNPGSKL IVLQQRLTGD VLKNAVAHAD
     VVLDCTDNMA TRQEINAACV ALNTPLITAS AVGFGGQLMV LTPPWEQGCY RCLWPDDVEP
     ERNCRTAGIV GPVVGMMGTL QALEAIKLLS GIETPSGELR LFDGKTSQWR SLALRRASGC
     PVCGGRHANS VQ
//