ID Q57XC3_TRYB2 Unreviewed; 1919 AA.
AC Q57XC3; D6XL03;
DT 10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAX69744.1};
GN Name=Tb08.26A17.710 {ECO:0000313|EMBL:AAZ13033.1};
GN ORFNames=Tb927.8.2660 {ECO:0000313|EMBL:AAX69744.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:AAX69744.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:AAZ13033.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ13033.1};
RX PubMed=16020724; DOI=10.1126/science.1112181;
RA El-Sayed N.M., Myler P.J., Blandin G., Berriman M., Crabtree J.,
RA Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C.,
RA Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.N.,
RA Wortman J.R., Alsmark U.C., Angiuoli S., Anupama A., Badger J.,
RA Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T.,
RA Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C.,
RA Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L.,
RA Shallom J., Silva J.C., Sundaram J., Westenberger S., White O.,
RA Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N.;
RT "Comparative genomics of trypanosomatid parasitic protozoa.";
RL Science 309:404-409(2005).
RN [2] {ECO:0000313|EMBL:AAZ13033.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ13033.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
RN [3] {ECO:0000313|EMBL:AAX69744.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX69744.1};
RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L.,
RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J.,
RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.,
RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O.,
RA Wortman J., Fraser C.M., El-Sayed N.M.A.;
RT ".";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AAZ13033.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ13033.1};
RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L.,
RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J.,
RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.,
RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O.,
RA Wortman J., Fraser C.M., El-Sayed N.M.A.;
RT "Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2
RT through 8.";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AC159420; AAX69744.1; -; Genomic_DNA.
DR EMBL; CP000071; AAZ13033.1; -; Genomic_DNA.
DR RefSeq; XP_847099.1; XM_842006.1.
DR AlphaFoldDB; Q57XC3; -.
DR STRING; 185431.Q57XC3; -.
DR PaxDb; 5691-AAZ13033; -.
DR GeneID; 3659249; -.
DR KEGG; tbr:Tb927.8.2660; -.
DR VEuPathDB; TriTrypDB:Tb927.8.2660; -.
DR eggNOG; KOG4693; Eukaryota.
DR InParanoid; Q57XC3; -.
DR OrthoDB; 152489at2759; -.
DR Proteomes; UP000008524; Chromosome 8.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR23244; KELCH REPEAT DOMAIN; 1.
DR PANTHER; PTHR23244:SF471; KELCH REPEAT-CONTAINING PROTEIN 1-RELATED; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524}.
FT REGION 138..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1290..1326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1450..1476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1730..1783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1816..1919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..394
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1294..1314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1454..1473
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1884..1898
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1919 AA; 209696 MW; B141D34302179625 CRC64;
MSVTVNAVRE SAEAVSLTIL SCEPAQQKIA VRFGGSHGGW RWIDVPTNTP VILERMRPEA
GAESSEGPTS NGAAMEGCEE YELAVTPSPP VDGRDESVCS LVGVDTRQVV QKPVLLSGAD
EGGRVFELLL KWTLLDATPT PRESTPDKAP EDHSGTETET RNEEEVIVDT ANKDDEKGEE
APPPPPIVAQ PDESKEKEIS ENPSGHDSPK DKRVERHVNP VKELEEPKQQ EAEREPQQEQ
APQPRCNQSE WKWKSSVIPT LPADVSAARH VLIATIVSVQ QPAVLPNRHV VVKLGIEAPN
ERMSLLPLLR TRAVTQYDAV KVAQMGPPVL FPLSENVSVY CAVADKRADH PSDSGGIGRR
VYRRGRPAPT KSPGRSLARI PKAELDKHAA EKASKPHTAT SGECTFSLPQ RIEGTGNSDN
AGGGRNGGAS VFHWEKHSHM EHAYIAHGTV QCGNNEVELA FLRMTVGAYR DACRGHGAAR
RNGFGTVEVR VEDIELNETT EKQRPEHDNT LVEVWLTQPE VDAVSGTHSD RTGAAAAAST
STKNSSGCRH LVLLSSSNCI QPLHFPVSEP FAYLSWAVVP AQQKQGVQEN VLHGAAPICL
VRPGVWTPIT IKLRDRNKSA SFIKLWYCFT SDGRSGMDDP SRPYHPASKS TDDGNCYSLR
VYLDSCTNLY PLVQLYSRDG NAKAFRLLIM DPEDEVAVSA SRPMDLNDMQ LYCNYKGGED
RTPPAIKLLF TRVFPSHALY RSSDYTVSNT GEQAGTCSVT FLCRLFAFAS VAEAHAMNNA
HCIGEGRVVV FPGNVVNGKD GTNLDIDVHV AVDGMFTPGP VAVKPTAVTS PPPCTVLRMR
GEVERAPCGE GDAVICVRSV QLFHRQQQQK RRGRVVWTDG GLSAVYACFW LCRGLSGGGV
KEWKEALKGC QVLTLTPKQQ RHHHHQQQQE VSLQCNEFVL STGGEKLVLC AVFIPKTTET
VDDEAKVRNT ASNLLRKLVR KVNKKKQESE SGLRHVQGTM RALNYLEVDL TLSAAAQGAV
VGTAHINDEL LLQLKAAWVK VPSGVGAATV PRGSATQPVD QPSPHLWALR LTFPTQPARS
HVNVHVKSWP VAYDDLSHEQ QQTFNSNLVK AHRGGGAATK VDSTMSSAFY IVRPLRLEPA
EGEWTLFIFG DACTTRTRLA ASVGETVLEH VVVDYLLPQS LSLAKGVIVD CFHGSLHADE
AGELKRRAEG EQRWRRKLRE DPSIQQPCQL FVPFTSLAIS ADGSDPVTLR YHTLTRCTDD
GALLIGAATS NGKGAIFHYN INENTWSVLP IRAPQDGKDK KRREQGKRDN NGAEDADNSQ
QASHFSTRCI TSRHGHTTVC SSTEKCAYVY GGIGIGGTDP EAATAAVAES NRSDKSAALS
PKLGSTSSPK WPVGFMRDIW CINYAEGTAT CLCSGENQTV SAPISRWRHA AAFHNDSVII
IGGRTAPALQ QEGAKETNEE KLLTEEETQK KQEDGQTFYQ SHGGEEEDLL LRRDGLCSCC
SLLVFDLNRR AWGTQTTSGA TPAPRYGHAS AVLGTCVYIF GGMTQRNHLL DDLHELDIAT
NTWRRVEYNG AVAPPPSHLA AMEAITVSNT PCLVLTVGAA GNGEEREAGD AAERGVDALR
LYLFSHASQF WRRLRFNCAP LPAPVGVAMC DATPASMRQH GRRQQPLRHR SLPLNKAVLF
RMLVVGGMKA GSPNKGSAYI ADYGLEREST IRPVVPTLLN VARDVIAERR QDERREPPHS
ADLRNINLER SPIRKGIGQR TASSLCTTPR GARSGRKPYK SGPLKIAYRS SSAGPLTQDQ
QRGLIHRLYY NQCHAQEERK KGELQEQPRS GKMPISGRKY NPHPPMQRKA WGAPAAPRAD
CMRPRKPATA GPYRNHRHLD SSGDTQIKPQ NDSRGEELTA TAPPTPVVAA GRRLSDPEN
//
