ID Q58E11_XENLA Unreviewed; 204 AA.
AC Q58E11;
DT 26-APR-2005, integrated into UniProtKB/TrEMBL.
DT 26-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN Name=MGC146443.L {ECO:0000313|RefSeq:NP_001089336.1,
GN ECO:0000313|Xenbase:XB-GENE-6487975};
GN Synonyms=MGC115038 {ECO:0000313|EMBL:AAH92118.1}, mgc146443
GN {ECO:0000313|Xenbase:XB-GENE-6487975}, mgc146443.L
GN {ECO:0000313|Xenbase:XB-GENE-6487975};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH92118.1};
RN [1] {ECO:0000313|RefSeq:NP_001089336.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH92118.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye {ECO:0000313|EMBL:AAH92118.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001089336.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
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DR EMBL; BC092118; AAH92118.1; -; mRNA.
DR RefSeq; NP_001089336.1; NM_001095867.1.
DR DNASU; 734386; -.
DR GeneID; 734386; -.
DR KEGG; xla:734386; -.
DR AGR; Xenbase:XB-GENE-6487975; -.
DR CTD; 734386; -.
DR Xenbase; XB-GENE-6487975; MGC146443.L.
DR OrthoDB; 3280806at2759; -.
DR Proteomes; UP000186698; Chromosome 5S.
DR Bgee; 734386; Expressed in testis and 10 other cell types or tissues.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd09280; RNase_HI_eukaryote_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.40.970.10; Ribonuclease H1, N-terminal domain; 1.
DR InterPro; IPR009027; Ribosomal_bL9/RNase_H1_N.
DR InterPro; IPR011320; RNase_H1_N.
DR InterPro; IPR037056; RNase_H1_N_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF01693; Cauli_VI; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF55658; L9 N-domain-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 57..203
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
SQ SEQUENCE 204 AA; 23016 MW; C330CD5C304EB97D CRC64;
MPYGVRRGRQ TGVYDTWEEC REQVDCYPQA SFKKLPTYGE ARDFVETRER NSSYSSAGRS
AEVYTDGCCS RNGQYGANGG IGVYWGPNDS RNVSARLEGR QTNQRAEIEA AYTAAKQARN
DNVTHLEINT DSKFTIDGMT KWVPRWKENN WKTIDGRDVI NKQDFQKLDK ACENMDVKWN
YVPGHSGNAG NEMADQLAKA GSSK
//
