ID   Q58LI2_BPPRS            Unreviewed;       487 AA.
AC   Q58LI2;
DT   26-APR-2005, integrated into UniProtKB/TrEMBL.
DT   26-APR-2005, sequence version 1.
DT   24-JAN-2024, entry version 89.
DE   SubName: Full=RNA-DNA + DNA-DNA helicase {ECO:0000313|EMBL:AAX46917.1};
GN   Name=uvsW {ECO:0000313|EMBL:AAX46917.1};
GN   ORFNames=PSSM4_116 {ECO:0000313|EMBL:AAX46917.1};
OS   Prochlorococcus phage P-SSM4.
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Kyanoviridae; Ronodorvirus; Ronodorvirus ssm4.
OX   NCBI_TaxID=268747 {ECO:0000313|EMBL:AAX46917.1, ECO:0000313|Proteomes:UP000000915};
OH   NCBI_TaxID=1218; Prochlorococcus.
RN   [1] {ECO:0000313|EMBL:AAX46917.1, ECO:0000313|Proteomes:UP000000915}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15828858; DOI=10.1371/journal.pbio.0030144;
RA   Sullivan M.B., Coleman M.L., Weigele P., Rohwer F., Chisholm S.W.;
RT   "Three Prochlorococcus cyanophage genomes: signature features and
RT   ecological interpretations.";
RL   PLoS Biol. 3:E144-E144(2005).
RN   [2] {ECO:0000313|EMBL:AAX46917.1, ECO:0000313|Proteomes:UP000000915}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20662890; DOI=10.1111/j.1462-2920.2010.02280.x;
RA   Sullivan M.B., Huang K.H., Ignacio-Espinoza J.C., Berlin A.M., Kelly L.,
RA   Weigele P.R., DeFrancesco A.S., Kern S.E., Thompson L.R., Young S.,
RA   Yandava C., Fu R., Krastins B., Chase M., Sarracino D., Osburne M.S.,
RA   Henn M.R., Chisholm S.W.;
RT   "Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-
RT   like myoviruses from diverse hosts and environments.";
RL   Environ. Microbiol. 12:3035-3056(2010).
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DR   EMBL; AY940168; AAX46917.1; -; Genomic_DNA.
DR   RefSeq; YP_214677.1; NC_006884.2.
DR   GeneID; 3294597; -.
DR   KEGG; vg:3294597; -.
DR   OrthoDB; 2008at10239; -.
DR   Proteomes; UP000000915; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd17926; DEXHc_RE; 1.
DR   Gene3D; 3.30.780.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049409; UvsW_N.
DR   InterPro; IPR049430; UvsW_N_sf.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   Pfam; PF21241; UvsW_N; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:AAX46917.1};
KW   Helicase {ECO:0000313|EMBL:AAX46917.1};
KW   Hydrolase {ECO:0000313|EMBL:AAX46917.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:AAX46917.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000915}.
FT   DOMAIN          125..278
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          328..487
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   487 AA;  56615 MW;  21B2473ABAF9CF52 CRC64;
     MDLLISKKNE VYLKIEAQPH INYELSDFFT FEVESAKYMQ KTRRYKGWDG KIRLYSPANG
     EIYCGLIDYL TDWADKKGYD YVLDEDEFYG HPQETNDLIT PEGVASFVQS LHLNHRVRDY
     QYQAIYECLK YNRRLLLSPT ASGKSLMIYS LVRYHVNADR NVLIVVPTTS LVEQMYKDFK
     EYGWNVGHHC HKLYAGAEKY TEHDVVISTW QSIYKEPKKW FDKFDCVIGD EAHLFKAKSL
     TSLMGKLHDC KYRIGFTGTL DGANVNQLVL EGVFGKCSKV TKTNELMKQG YLSKLKVKIV
     LIKHKEKLFE GYQDEMDYLV EHEPRNKFIK NLAKDLKGNT LILFNYVEKH GLPLYNMINS
     DTERPVYFVH GGVDTEDREE IRLLTEKSDN SIIVASYGTF STGINIRNLH NVIFASPSKS
     RIRNLQSIGR VLRKGDNKSK ATLYDIADDI STDKGNNYTL NHLLERVKIY NEEKFDYEII
     DVKLKDD
//