ID   Q59HH5_HUMAN            Unreviewed;       742 AA.
AC   Q59HH5;
DT   26-APR-2005, integrated into UniProtKB/TrEMBL.
DT   26-APR-2005, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   RecName: Full=Oviduct-specific glycoprotein {ECO:0000256|ARBA:ARBA00039807};
DE   AltName: Full=Estrogen-dependent oviduct protein {ECO:0000256|ARBA:ARBA00042450};
DE   AltName: Full=Oviductal glycoprotein {ECO:0000256|ARBA:ARBA00042898};
DE   AltName: Full=Oviductin {ECO:0000256|ARBA:ARBA00043205};
DE   Flags: Fragment;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAD92020.1};
RN   [1] {ECO:0000313|EMBL:BAD92020.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Brain {ECO:0000313|EMBL:BAD92020.1};
RA   Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.,
RA   Ohara O., Nagase T., Kikuno R.F.;
RT   "Homo sapiens protein coding cDNA.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle
CC       {ECO:0000256|ARBA:ARBA00004398}. Vesicle
CC       {ECO:0000256|ARBA:ARBA00004373}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC       {ECO:0000256|ARBA:ARBA00009336}.
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DR   EMBL; AB208783; BAD92020.1; -; mRNA.
DR   AlphaFoldDB; Q59HH5; -.
DR   PeptideAtlas; Q59HH5; -.
DR   GO; GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR   CDD; cd02872; GH18_chitolectin_chitotriosidase; 1.
DR   Gene3D; 3.10.50.10; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11177; CHITINASE; 1.
DR   PANTHER; PTHR11177:SF385; OVIDUCT-SPECIFIC GLYCOPROTEIN; 1.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Fertilization {ECO:0000256|ARBA:ARBA00023279}.
FT   DOMAIN          64..449
FT                   /note="GH18"
FT                   /evidence="ECO:0000259|PROSITE:PS51910"
FT   REGION          588..608
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          645..670
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          715..742
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        645..660
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        715..730
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:BAD92020.1"
SQ   SEQUENCE   742 AA;  82471 MW;  C8329B44A7D14B4D CRC64;
     DLSSGGGIEP QCSSEVYFRA RERGCENVAW SLGLRSHCFL EAELHPLPWF LPTNVCSPLP
     GAAHKLVCYF TNWAHSRPGP ASILPHDLDP FLCTHLIFAF ASMNNNQIVA KDLQDEKILY
     PEFNKLKERM WQQLPTGVKN PAHQPSLSHH RNRELKTLLS IDGWNFGTSR FTTMLSTFAN
     REKFIASVIS LLRTHDFDGL DLFFLYPGLR GSPMHDRWTF LFLIEELLFA FRKEALLTMR
     PRLLLSAAVS GVPHIVQTSY DVRFLGRLLD FINVLSYDLH GSWERFTGHN SPLFSLPEDP
     KSSAYAMNYW RKLGAPSEKL IMGIPTYGRT FRLLKASKNG LQARAIGPAS PGKYTKQEGF
     LAYFEICSFV WGAKKHWIDY QYVPYANKGK EWVGYDNAIS FSYKAWFIRR EHFGGAMVWT
     LDMDDVRGTF CGTGPFPLVY VLNDILVRAE FSSTSLPQFW LSSAVNSSST DPERLAVTTA
     WTTDSKILPP GGEAGVTEIH GKCENMTITP RGTTVTPTKE TVSLGKHTVA LGEKTEITGA
     MTMTSVGHQS MTPGEKALTP VGHQSVTTGQ KTLTSVGYQS VTPGEKTLTP VGHQSVTPVS
     HQSVSPGGTT MTPVHFQTET LRQNTVAPRR KAVAREKVTV PSRNISVTPE GQTMPLRGEN
     LTSEVGTHPR MGNLGLQMEA ENRMMLSSSP VIQLPEQTPL AFDNRFVPIY GNHSSVNSVT
     PQTSPLSLKK EIPENSAVDE EA
//