ID Q5ATP3_EMENI Unreviewed; 351 AA.
AC Q5ATP3; C8VE30;
DT 26-APR-2005, integrated into UniProtKB/TrEMBL.
DT 26-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=High affinity zinc ion transporter, putative (AFU_orthologue AFUA_1G01550) {ECO:0000313|EMBL:CBF80336.1};
GN ORFNames=ANIA_08337 {ECO:0000313|EMBL:CBF80336.1};
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF80336.1, ECO:0000313|Proteomes:UP000000560};
RN [1] {ECO:0000313|Proteomes:UP000000560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R., Batzoglou S.,
RA Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M., Hynes M., Paoletti M., Fischer R., Miller B.,
RA Dyer P., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2] {ECO:0000313|Proteomes:UP000000560}
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362088}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362088}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000256|ARBA:ARBA00006939, ECO:0000256|RuleBase:RU362088}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362088}.
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DR EMBL; BN001305; CBF80336.1; -; Genomic_DNA.
DR RefSeq; XP_681606.1; XM_676514.1.
DR AlphaFoldDB; Q5ATP3; -.
DR STRING; 227321.Q5ATP3; -.
DR EnsemblFungi; CBF80336; CBF80336; ANIA_08337.
DR GeneID; 2868831; -.
DR KEGG; ani:AN8337.2; -.
DR VEuPathDB; FungiDB:AN8337; -.
DR eggNOG; KOG1558; Eukaryota.
DR HOGENOM; CLU_027089_0_2_1; -.
DR InParanoid; Q5ATP3; -.
DR OMA; TGGWAEY; -.
DR OrthoDB; 1112460at2759; -.
DR Proteomes; UP000000560; Chromosome V.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0000006; F:high-affinity zinc transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0071578; P:zinc ion import across plasma membrane; IBA:GO_Central.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR004698; Zn/Fe_permease_fun/pln.
DR NCBIfam; TIGR00820; zip; 1.
DR PANTHER; PTHR11040:SF32; ZINC-REGULATED TRANSPORTER 1; 1.
DR PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR Pfam; PF02535; Zip; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU362088};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362088};
KW Reference proteome {ECO:0000313|Proteomes:UP000000560};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362088};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362088}; Transport {ECO:0000256|RuleBase:RU362088}.
FT TRANSMEM 37..56
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362088"
FT TRANSMEM 68..89
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362088"
FT TRANSMEM 109..131
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362088"
FT TRANSMEM 195..214
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362088"
FT TRANSMEM 255..278
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362088"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362088"
FT TRANSMEM 330..348
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362088"
SQ SEQUENCE 351 AA; 38480 MW; 49465E82A21422C5 CRC64;
MSFNPNSVDL DTADPRDVIC YMNAGENDYD GRLGARISAI FVIFVVSTAV TFFPMLAKRN
PRLHIPHYVY LFARYFGAGV IVATAFIHLL DPAYDEIGPA SCVGMTGHWA DYSWCPAIVL
ASVMGIFLLD FGAERYVEIK YGVCREDPEQ FMTSTANNEE AVSRQATSTG KKAGDTLEAQ
SIDSGYIERS FRQQIAAFLI LEFGIIFHSV IIGLNLGTTG EEFPTLYPVL VFHQSFEGLG
IGARMSAIPF RKGSWLPWAL CLLYGLTTPI AIAIGLGVRT TYNAGSFTAN VVSGIFDAIS
AGVLIYTGLV ELLARDFLFD PHRTQDSKRL TFMVISLLWG AGIMALIGKW A
//
