ID Q5B9M9_EMENI Unreviewed; 819 AA.
AC Q5B9M9; C8VJX4;
DT 26-APR-2005, integrated into UniProtKB/TrEMBL.
DT 26-APR-2005, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE SubName: Full=Topisomerase II associated protein (Pat1), putative (AFU_orthologue AFUA_5G10770) {ECO:0000313|EMBL:CBF84090.1};
GN ORFNames=ANIA_02751 {ECO:0000313|EMBL:CBF84090.1};
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF84090.1, ECO:0000313|Proteomes:UP000000560};
RN [1] {ECO:0000313|Proteomes:UP000000560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R., Batzoglou S.,
RA Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M., Hynes M., Paoletti M., Fischer R., Miller B.,
RA Dyer P., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2] {ECO:0000313|Proteomes:UP000000560}
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC {ECO:0000313|Proteomes:UP000000560};
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the PAT1 family.
CC {ECO:0000256|ARBA:ARBA00009138}.
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DR EMBL; BN001306; CBF84090.1; -; Genomic_DNA.
DR RefSeq; XP_660355.1; XM_655263.1.
DR AlphaFoldDB; Q5B9M9; -.
DR STRING; 227321.Q5B9M9; -.
DR EnsemblFungi; CBF84090; CBF84090; ANIA_02751.
DR GeneID; 2874475; -.
DR KEGG; ani:AN2751.2; -.
DR VEuPathDB; FungiDB:AN2751; -.
DR eggNOG; KOG4592; Eukaryota.
DR HOGENOM; CLU_012622_1_0_1; -.
DR InParanoid; Q5B9M9; -.
DR OMA; YLEHSGH; -.
DR OrthoDB; 2786412at2759; -.
DR Proteomes; UP000000560; Chromosome VI.
DR GO; GO:0000932; C:P-body; IDA:AspGD.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IBA:GO_Central.
DR GO; GO:0033962; P:P-body assembly; IBA:GO_Central.
DR InterPro; IPR039900; Pat1-like.
DR InterPro; IPR019167; PAT1_dom.
DR PANTHER; PTHR21551:SF0; PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A; 1.
DR PANTHER; PTHR21551; TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1; 1.
DR Pfam; PF09770; PAT1; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000000560}.
FT DOMAIN 1..816
FT /note="mRNA decay factor PAT1"
FT /evidence="ECO:0000259|Pfam:PF09770"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 110..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 272..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 819 AA; 90760 MW; 2F3D9A5A515D0ACF CRC64;
MSFFGFDTTL PRDRAPQGGQ RGIFDTPDPF AEVARARAAA QHEDDDDVLN FEDTYDGLGD
QLDDDQDAFN EDTFGDVGSG PVGKDFDFFG KTAQVSDVIG EEQVRYNLKN PQASVAPRAT
EPQKTATTTA QQPKRTGYEK YSDPDYIPDL QAKSSVWGLP SKPESAPQAT TQTKKMMSLE
EVEAQIRNQG AAAPGFGPQV SLPQHVPEPP LPLQRPPGLP EGFPQLPPEY LEAQFGRGVP
PQFLHPRTIA PEPFPHPAQA PNIPLHLLQN PIQNPNAPPS HMGPLQHQAI PSRDQPPQRL
PQQHLPQHGR GLSAGLPLIT NPQQLMNLTE EQRVAYLMED AKRAKRNHKI FLLSKGNGLM
TPQDKNFITR IQLQQLVAQA GNMADTDSDA VLAEDFYYQV YSQIRGAPRQ HPHQPLGHFA
QTYLLQTGNR IGGHSRKHGQ SADNHMQRMQ QQVQRAVEAA KAKPKNKQLI IEGSLGKISF
GNAKAPKPSL NIKRPESSEG GKATKKLPTD LSPSDRKSIL ANLEGVYNTL MELEDMARTM
PPPPDENDSE AIQTHMEWRQ KLNALNQKLW NQMKVMEAIV PNSNTPHPFI ALLSYPKGKK
AIPRIFRHID QEQRITILTM IVVNLDNLDV VRRALPAPGE AQPPLAAREA IDLFSQAVMP
CLLGYVNEAP FNIIIGLLGL VLTHTHAQFV ARTRIGLGIL TMLLSRAEIV KEAGQASEQD
WKQWVEKFNI LFDTLEPTFA DIFPNSINAG DDMYVWQFLA AIGIGASPEQ QQRLVIAVKD
RVMETVTHSK TLPADMASQR LGNVNLFMRA IGLDVELLG
//
