ID Q5CQK2_CRYPI Unreviewed; 367 AA.
AC Q5CQK2;
DT 12-APR-2005, integrated into UniProtKB/TrEMBL.
DT 12-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Protein with 8 transmembrane domains, possible amino alcohol phosphotransferase {ECO:0000313|EMBL:EAK87730.1};
DE Flags: Fragment;
GN ORFNames=cgd4_390 {ECO:0000313|EMBL:EAK87730.1};
OS Cryptosporidium parvum (strain Iowa II).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK87730.1, ECO:0000313|Proteomes:UP000006726};
RN [1] {ECO:0000313|EMBL:EAK87730.1, ECO:0000313|Proteomes:UP000006726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX PubMed=15044751; DOI=10.1126/science.1094786;
RA Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA Anantharaman V., Aravind L., Kapur V.;
RT "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL Science 304:441-445(2004).
CC -!- SIMILARITY: Belongs to the CDP-alcohol phosphatidyltransferase class-I
CC family. {ECO:0000256|ARBA:ARBA00010441, ECO:0000256|RuleBase:RU003750}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAK87730.1}.
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DR EMBL; AAEE01000009; EAK87730.1; -; Genomic_DNA.
DR RefSeq; XP_625646.1; XM_625646.1.
DR AlphaFoldDB; Q5CQK2; -.
DR STRING; 353152.Q5CQK2; -.
DR EnsemblProtists; EAK87730; EAK87730; cgd4_390.
DR GeneID; 3372661; -.
DR KEGG; cpv:cgd4_390; -.
DR InParanoid; Q5CQK2; -.
DR OMA; ISIMTIG; -.
DR OrthoDB; 198583at2759; -.
DR Proteomes; UP000006726; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1760; -; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR InterPro; IPR048254; CDP_ALCOHOL_P_TRANSF_CS.
DR InterPro; IPR014472; CHOPT.
DR PANTHER; PTHR10414:SF37; BB IN A BOXCAR, ISOFORM C; 1.
DR PANTHER; PTHR10414; ETHANOLAMINEPHOSPHOTRANSFERASE; 1.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
DR PROSITE; PS00379; CDP_ALCOHOL_P_TRANSF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006726};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003750};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:EAK87730.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAK87730.1"
SQ SEQUENCE 367 AA; 41893 MW; 72B85F2A30204F96 CRC64;
ENKVISVPIK MKETGVESKN VSGKHEEYKY VQPMTSPLYN NVISPVCDKI VGFLPKYLSP
NLLTIIGLIS ISTSFIMLIS IGENSKKLYF VSAALWFLYG IIDNLDGKQA RRLGVSSNSG
EFIDHAIDSV VTSFVGLAFQ YMHNRYLELD LLVVLSYQLP FYFACWFHFK YGKLIIGNSV
SKTPYFTVDE LNLVFVPLFI LFEYLFPGLW NLDIPLYGGY IIKSWGIPFN YCCFIYSIFT
LLSCLHYCLS KSLTNAHLLF IPLTIHVTSK ELAKLSMYNT ILPFSILCIT FIFLKISKLL
IKKPTRSFIT LIGASLIPNI TTKLLVSVFE INQNLTIFIQ FLIWALLVYE FANYLDSPCE
DAEDKKK
//
