ID   Q5CW51_CRYPI            Unreviewed;      2120 AA.
AC   Q5CW51;
DT   12-APR-2005, integrated into UniProtKB/TrEMBL.
DT   12-APR-2005, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Sacsin like HSP90 chaperone domain, likely plant origin {ECO:0000313|EMBL:EAK89372.1};
GN   ORFNames=cgd8_1610 {ECO:0000313|EMBL:EAK89372.1};
OS   Cryptosporidium parvum (strain Iowa II).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK89372.1, ECO:0000313|Proteomes:UP000006726};
RN   [1] {ECO:0000313|EMBL:EAK89372.1, ECO:0000313|Proteomes:UP000006726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX   PubMed=15044751; DOI=10.1126/science.1094786;
RA   Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA   Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA   Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA   Anantharaman V., Aravind L., Kapur V.;
RT   "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL   Science 304:441-445(2004).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAK89372.1}.
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DR   EMBL; AAEE01000003; EAK89372.1; -; Genomic_DNA.
DR   RefSeq; XP_627068.1; XM_627068.1.
DR   STRING; 353152.Q5CW51; -.
DR   EnsemblProtists; EAK89372; EAK89372; cgd8_1610.
DR   GeneID; 3374480; -.
DR   KEGG; cpv:cgd8_1610; -.
DR   VEuPathDB; CryptoDB:cgd8_1610; -.
DR   InParanoid; Q5CW51; -.
DR   OMA; NIKCCER; -.
DR   OrthoDB; 1782746at2759; -.
DR   Proteomes; UP000006726; Chromosome 8.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR024975; NOV_C.
DR   PANTHER; PTHR32387:SF0; PROTEIN NO VEIN-RELATED; 1.
DR   PANTHER; PTHR32387; WU:FJ29H11; 1.
DR   Pfam; PF13020; NOV_C; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006726}.
FT   DOMAIN          1990..2078
FT                   /note="Protein NO VEIN C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13020"
SQ   SEQUENCE   2120 AA;  246066 MW;  DB5F22FE7C1FD936 CRC64;
     MQNEQTKKHI QEIRESLFVS NKSQRDRQDR SIGILSNELY SSFGRVLLEL LQNADDSNFN
     FNEIGEGIPQ VYILLRWDCL VFHINEKGMT RENIESVCDI GNSSKKNSES RYFTGEKGIG
     YRSIFKITDN PCIFSGGYSI KFSSKPDEEI ELSYIVPKWI EESDFPEVVK TIHSNISLYG
     TPWRFDNIRS EFGPKFVQSS SNLGTLHYLP FEKNMKQKFS SILSAIRNTF VHDILLFLRN
     IKSIVVDVEP RKDSDFCSFE KNTIYPLLRR RLTLNDLISV PDISQSLGET FNLDEFKDDS
     LSSIKSFRFT KIEIAQFDDD DLDLNKGKLL RESLISSKYL IVDWEIPISE DQKLESSTLR
     DRATRSSTVW SIALPLFHSN LRLEIDKGER IINSSSFSFG SSTFGKHKRV TGKLFCTFPL
     NHRIYLPFHV NIQDLILTAN REDVMADNIW NSTILDVIFK KQIPQFVASM INPKLSCSRK
     SCLINQKYSL FMSNLLTSKS LPLQTMQESS FDYNLKPFVL NTSEFIKFSW LPPKLDNLNQ
     CQNYCTLSSI CIDELVKKPV FMNIDGSFCF LDKISTNIQF NDLCIKNNTF HEGFCIFCNL
     HWNFLYMLSV HMRPVLHPSL IGGHTCMHFL CTRPLQMLQV LVAQIISSYN VRNLDILKIF
     LELKPLKFLE SISDEELLIL YSYLFPQKEG DVESLKEFEG ISGLPIIPTR EGKRVSIEKS
     SIVKVYISDE SFDSYFQEHC LQKYSEIIGK VCPFEFFSDR VYKIAPYRIK SMINQDFKIE
     KITPSIFFKL IAEQVDLLLE KGWENAINSD IQKLLLKITP LAIEEASIVE DDNRFLIKLP
     IVVQTYSPSF LKALLYNKDL PKSYANEEEL LNKNKLARCS RMITSSLKCN RCKNETRENE
     VMVYPTSVAL RMSQVSKSLT SLILLHSSWE RSNKFSSKSY SNFDQLKTSN SNRKNVKDKT
     SIYNSDKSFE YKGLTIVPPL WPPLVEWVFP KVSDRFHFVE ISSDYIVQNS DHLNENDKDL
     AFRVFTNKFI NLLEQWYVGC NFDRLPPKTD ASPLSWMVDR NIYPISSSHC FYCKHLIYVM
     RAGAIIQIAN EYSRRSYNSS FLNEILSSYP WIPISLYNDN YFSYYMSQIN NEQIQDCDTV
     DFCEDLLLSR PSELFIPKIN KNLDGIIKHI SQIVLNLLPV TLRNGYKIPK SRENNEPCSA
     HYTLNRTEED IGNESKLISE TLEEVGVTTQ ISSISLIRIL RDYKRVMNIR DNEVVQKSRQ
     IKLKPSYDPD LNHIIELAIF GFGITKEKLF ASDWWPSLMD EWSNFDDNSL NRSLHRPSDI
     EMISDIYHIL GHQTDFDISM NIKKVFYNES LLYIPLMKST LYNWVPIDYN NMVWSDPYDF
     FHGTFIVLSK FINKSKISNL RPFFLSLVSE QPIHHHYAYL WLRECPNLLK DESKEGKIKF
     ESFINVSINT FLKVFQKMSQ SKKNSWWSEF LDNAKIPIKG IYKFLKREQC CVEDFPIGSL
     RSDSFQIPLA ISSSPSSQFF YKDILKVKTL SECYKVTYKV NYGRNIRSHI KFANKGKNKI
     WLTLEFWGIL ILLFKHKSLD IYLSIMRILE EKKTFDSEQS LTSKNSNHSV TDCEFCVSES
     EILEQISNSY EFEPLSVSER YSNANEEIAY QIANWLISFV NTYEVEVDDI ELKFDLNIND
     KHLPKTSRRK IGVLFRQIPN KNSASILLVN KSMDKSNQLK DLYTLLLDPL KGLTGLNSII
     NIDLYELLIL SSSQRLLLLS KHVPILDDLS SKRDERFTVD NVVKEGFELL KKCSRSGCLL
     RKDTDIENKS LHVEKNDLLS ELSIKRVDYN KADNNDPHIK VKNNNTGDYK EMTKNTDVIE
     SNLDSIIKEY IKKNPLSLGN ATDESLTIEE ITKMVGFWGE KVSFEAIIPN AISRKLTLKS
     IDHNLIEDYL SRKFVNNYIQ NEVIDMEDLK DWTGIEDMKI EDNNIFQDQQ RDLFIKCKIK
     CFKESDTTTI KLIWLNSLNE SFLPFDFILL REYFSEEEFS VSRNYKQQVL ALIEVKTTKL
     PIWQFNISGN ELLSARKAVD KFKLLIIKDA GSSEPQWALI DDVGGFIQES CTLINGVFEA
     NFSDFCGFNS NTSGVLDNMY
//