ID Q5D9X4_SCHJA Unreviewed; 288 AA.
AC Q5D9X4;
DT 29-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 29-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Eukaryotic translation initiation factor 4H {ECO:0000313|EMBL:CAX74643.1};
DE SubName: Full=Putative RNA-binding protein {ECO:0000313|EMBL:TNN21096.1};
DE SubName: Full=SJCHGC09499 protein {ECO:0000313|EMBL:AAW27382.1};
GN Name=eIF-4H {ECO:0000313|EMBL:CAX74643.1};
GN ORFNames=EWB00_000725 {ECO:0000313|EMBL:TNN21096.1};
OS Schistosoma japonicum (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6182 {ECO:0000313|EMBL:AAW27382.1};
RN [1] {ECO:0000313|EMBL:AAW27382.1}
RP NUCLEOTIDE SEQUENCE.
RA Han Z.;
RT "The full-length cDNA sequences of Schistosoma japonicum genes.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAW27382.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16617374; DOI=10.1371/journal.ppat.0020029;
RA Liu F., Lu J., Hu W., Wang S.Y., Cui S.J., Chi M., Yan Q., Wang X.R.,
RA Song H.D., Xu X.N., Wang J.J., Zhang X.L., Zhang X., Wang Z.Q., Xue C.L.,
RA Brindley P.J., McManus D.P., Yang P.Y., Feng Z., Chen Z., Han Z.G.;
RT "New perspectives on host-parasite interplay by comparative transcriptomic
RT and proteomic analyses of Schistosoma japonicum.";
RL PLoS Pathog. 2:268-281(2006).
RN [3] {ECO:0000313|EMBL:CAX74643.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Anhui {ECO:0000313|EMBL:CAX74643.1};
RX DOI=10.1038/nature08140;
RA Liu F., Zhou Y., Wang Z.Q., Lu G., Zheng H., Brindley P.J., McManus D.P.,
RA Blair D., Zhang Q.H., Zhong Y., Wang S., Han Z.G., Chen Z.;
RT "The Schistosoma japonicum genome reveals features of host-parasite
RT interplay.";
RL Nature 460:345-351(2009).
RN [4] {ECO:0000313|EMBL:CAX74643.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Anhui {ECO:0000313|EMBL:CAX74643.1};
RA Gang L.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:TNN21096.1, ECO:0000313|Proteomes:UP000311919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HuSjv2 {ECO:0000313|EMBL:TNN21096.1};
RC TISSUE=Worms {ECO:0000313|EMBL:TNN21096.1};
RA Hu W., Luo F., Yin M., Mo X., Sun C., Wu Q., Zhu B., Xiang M., Wang J.,
RA Wang Y., Zhang T., Xu B., Zheng H., Feng Z.;
RT "An improved genome assembly of the fluke Schistosoma japonicum.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AY815650; AAW27382.1; -; mRNA.
DR EMBL; FN318915; CAX74643.1; -; mRNA.
DR EMBL; FN318916; CAX74644.1; -; mRNA.
DR EMBL; SKCS01000013; TNN21096.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5D9X4; -.
DR STRING; 6182.Q5D9X4; -.
DR Proteomes; UP000311919; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23236:SF11; EUKARYOTIC TRANSLATION INITIATION FACTOR 4B; 1.
DR PANTHER; PTHR23236; EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Initiation factor {ECO:0000313|EMBL:CAX74643.1};
KW Protein biosynthesis {ECO:0000313|EMBL:CAX74643.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000311919};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 76..150
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 206..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 288 AA; 31912 MW; 6819AAAD0562727B CRC64;
MGKKSKKNRF NQSVDVDIVY SSNTIAEMDP TDNLAELNLS SEKAEELQKI RAKLPTFTST
SSVESELAKL PMDKPFRAFV YNVSYLATGA DVEQFFSPLR VTNINIVSGS GGSRGFCFVD
FASREDLAKA LERSDSSLAG RQVNVRIAAP NSSERGGFVR EKHSGMRRTE VPFERRGGYK
PSVLRDDGED NESIWKRGFV SRTSDFGPSG LTLNRSQLSL DPNLRSTPPG ERPKLNLLPR
TVQRDSDGQI SERNSKIFGE ARPVDTASKN REVEQRLSAA DQTSILNP
//
