ID   Q5D9Y1_SCHJA            Unreviewed;       217 AA.
AC   Q5D9Y1;
DT   29-MAR-2005, integrated into UniProtKB/TrEMBL.
DT   29-MAR-2005, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   RecName: Full=Peptidase C1A papain C-terminal domain-containing protein {ECO:0000259|SMART:SM00645};
OS   Schistosoma japonicum (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6182 {ECO:0000313|EMBL:AAW27375.1};
RN   [1] {ECO:0000313|EMBL:AAW27375.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Han Z.;
RT   "The full-length cDNA sequences of Schistosoma japonicum genes.";
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAW27375.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=16617374; DOI=10.1371/journal.ppat.0020029;
RA   Liu F., Lu J., Hu W., Wang S.Y., Cui S.J., Chi M., Yan Q., Wang X.R.,
RA   Song H.D., Xu X.N., Wang J.J., Zhang X.L., Zhang X., Wang Z.Q., Xue C.L.,
RA   Brindley P.J., McManus D.P., Yang P.Y., Feng Z., Chen Z., Han Z.G.;
RT   "New perspectives on host-parasite interplay by comparative transcriptomic
RT   and proteomic analyses of Schistosoma japonicum.";
RL   PLoS Pathog. 2:268-281(2006).
CC   -!- SIMILARITY: Belongs to the peptidase C1 family.
CC       {ECO:0000256|ARBA:ARBA00008455}.
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DR   EMBL; AY815643; AAW27375.1; -; mRNA.
DR   AlphaFoldDB; Q5D9Y1; -.
DR   MEROPS; C01.062; -.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR013128; Peptidase_C1A.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   InterPro; IPR012599; Propeptide_C1A.
DR   PANTHER; PTHR12411:SF1000; CATHEPSIN B1, ISOFORM A; 1.
DR   PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   Pfam; PF08127; Propeptide_C1; 1.
DR   SMART; SM00645; Pept_C1; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   2: Evidence at transcript level;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..217
FT                   /note="Peptidase C1A papain C-terminal domain-containing
FT                   protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018614861"
FT   DOMAIN          90..217
FT                   /note="Peptidase C1A papain C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00645"
SQ   SEQUENCE   217 AA;  24412 MW;  E8269EC4AB63B63A CRC64;
     MLKIAVYIVS LFNLLEAHVT TRNNERIEPL SDEMISFINK HPNAGWKADK SDRFHSVDDA
     RILLGGRRED PNLREKRRPT VDHHDLNVEI PSHFDSRKKW PRCKSISQIR DQSQCGSSWA
     VSAVGAMSDR ICIQSGGKQS VELSAVDLIS CCKYCGSGCD GGFLGPSWDY WVLRGIVTGG
     SKENHTGCRP YPFPKCDHFV KGKYRACGDK LYKSPPR
//