ID Q5E952_BOVIN Unreviewed; 283 AA.
AC Q5E952; F1MF58;
DT 15-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 145.
DE SubName: Full=RALY heteroous nuclear ribonucleoprotein {ECO:0000313|Ensembl:ENSBTAP00000041837.2};
DE SubName: Full=RNA binding protein (Autoantigenic, hnRNP-associated with lethal yellow) short isoform {ECO:0000313|EMBL:AAX09085.1};
GN Name=RALY {ECO:0000313|EMBL:AAX09085.1,
GN ECO:0000313|Ensembl:ENSBTAP00000041837.2,
GN ECO:0000313|VGNC:VGNC:33706};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAX09085.1};
RN [1] {ECO:0000313|EMBL:AAX09085.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Pooled {ECO:0000313|EMBL:AAX09085.1};
RX PubMed=12140684; DOI=10.1007/s00335-001-2145-4;
RA Sonstegard T.S., Capuco A.V., White J., Van Tassell C.P., Connor E.E.,
RA Cho J., Sultana R., Shade L., Wray J.E., Wells K.D., Quackenbush J.;
RT "Analysis of bovine mammary gland EST and functional annotation of the Bos
RT taurus gene index.";
RL Mamm. Genome 13:373-379(2002).
RN [2] {ECO:0000313|EMBL:AAX09085.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Pooled {ECO:0000313|EMBL:AAX09085.1};
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000041837.2, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000041837.2,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSBTAP00000041837.2}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000041837.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM HNRPC family. RALY subfamily.
CC {ECO:0000256|ARBA:ARBA00008631}.
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DR EMBL; BT021068; AAX09085.1; -; mRNA.
DR RefSeq; NP_001014847.1; NM_001014847.1.
DR RefSeq; XP_005214588.1; XM_005214531.3.
DR RefSeq; XP_010809677.1; XM_010811375.2.
DR STRING; 9913.ENSBTAP00000041837; -.
DR PaxDb; 9913-ENSBTAP00000041837; -.
DR Ensembl; ENSBTAT00000044331.3; ENSBTAP00000041837.2; ENSBTAG00000016524.6.
DR GeneID; 504640; -.
DR KEGG; bta:504640; -.
DR CTD; 22913; -.
DR VEuPathDB; HostDB:ENSBTAG00000016524; -.
DR VGNC; VGNC:33706; RALY.
DR eggNOG; KOG0118; Eukaryota.
DR GeneTree; ENSGT00940000157601; -.
DR HOGENOM; CLU_079090_1_1_1; -.
DR OMA; RDINANC; -.
DR OrthoDB; 2876583at2759; -.
DR TreeFam; TF330974; -.
DR Proteomes; UP000009136; Chromosome 13.
DR Bgee; ENSBTAG00000016524; Expressed in myometrium and 107 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR CDD; cd12604; RRM_RALY; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR017347; hnRNP_C.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034502; RALY_RRM.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR13968; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR13968:SF6; RNA-BINDING PROTEIN RALY; 1.
DR Pfam; PF00076; RRM_1; 1.
DR PIRSF; PIRSF037992; hnRNP-C_Raly; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 21..92
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 198..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..277
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 283 AA; 30143 MW; 0C5142FF4B09D6EE CRC64;
MSLKIQTSNV TNKNDPKSIN SRVFIGNLNT AVVKKSDVET IFSKYGRVAG CSVHKGYAFV
QYANERHARA AVVGENGRVL AGQTLDINMA GEPKPNRPKG LKRAASAIYR LFDYRGRLSP
VPVPRAVPVK RPRVTVPLVR RVKTTIPVKL FARSTAITTG TAKIKLKSSE LQTIKTELTQ
IKSNIDALLG RLEQIAEEQK ANPDGKKKGE SSSGSGSGGG SGSSGTGGSS RPPAPPEDTA
SEAGTPQGEA QARDDGDEEG LLTHSEEELE HSQDTDVEDG ALQ
//
