ID Q5GT06_WOLTR Unreviewed; 227 AA.
AC Q5GT06;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Type IV secretory pathway, component VirB8 {ECO:0000313|EMBL:AAW70868.1};
GN OrderedLocusNames=Wbm0279 {ECO:0000313|EMBL:AAW70868.1};
OS Wolbachia sp. subsp. Brugia malayi (strain TRS).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Wolbachieae; Wolbachia.
OX NCBI_TaxID=292805 {ECO:0000313|EMBL:AAW70868.1, ECO:0000313|Proteomes:UP000000534};
RN [1] {ECO:0000313|EMBL:AAW70868.1, ECO:0000313|Proteomes:UP000000534}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TRS {ECO:0000313|Proteomes:UP000000534};
RX PubMed=15780005; DOI=10.1371/journal.pbio.0030121;
RA Foster J., Ganatra M., Kamal I., Ware J., Makarova K., Ivanova N.,
RA Bhattacharyya A., Kapatral V., Kumar S., Posfai J., Vincze T., Ingram J.,
RA Moran L., Lapidus A., Omelchenko M., Kyrpides N., Ghedin E., Wang S.,
RA Goltsman E., Joukov V., Ostrovskaya O., Tsukerman K., Mazur M., Comb D.,
RA Koonin E., Slatko B.;
RT "The Wolbachia genome of Brugia malayi: endosymbiont evolution within a
RT human pathogenic nematode.";
RL PLoS Biol. 3:599-614(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; AE017321; AAW70868.1; -; Genomic_DNA.
DR RefSeq; WP_011256478.1; NC_006833.1.
DR AlphaFoldDB; Q5GT06; -.
DR STRING; 292805.Wbm0279; -.
DR KEGG; wbm:Wbm0279; -.
DR eggNOG; COG3736; Bacteria.
DR HOGENOM; CLU_068461_1_1_5; -.
DR Proteomes; UP000000534; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR CDD; cd16424; VirB8; 1.
DR Gene3D; 3.10.450.230; VirB8 protein; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR007430; VirB8.
DR InterPro; IPR026264; VirB8/PtlE.
DR Pfam; PF04335; VirB8; 1.
DR PIRSF; PIRSF003299; VirB8_PtlE; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000534};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..225
FT /note="Bacterial virulence protein VirB8"
FT /evidence="ECO:0000259|Pfam:PF04335"
SQ SEQUENCE 227 AA; 26868 MW; E7FEAE1CB323B7AA CRC64;
MLKFFKREKS NDSLDKDIDW NSSRYSTIIA QRNILLLFTL ILLVAIFIGI LAIFKISTSS
TIEPFVIEIE KKSGIVQLVD PVTVKQYSAD EVLNNHFIAE YIKAREVFDP YNYNYNYYTK
VRLFSSPNVY NEFKNYIRLQ NMDDLLNLYS GFVKNDFKIR STQKLDDDTF QVRFTVEFTR
EDGSSIRKNK IVIMSYRYAP LEMNDQQRYV NPLGFQVTSY RVDDEYV
//
