ID Q5HLD5_STAEQ Unreviewed; 952 AA.
AC Q5HLD5;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Helicase, putative {ECO:0000313|EMBL:AAW52892.1};
GN OrderedLocusNames=SERP2052 {ECO:0000313|EMBL:AAW52892.1};
OS Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=176279 {ECO:0000313|EMBL:AAW52892.1, ECO:0000313|Proteomes:UP000000531};
RN [1] {ECO:0000313|EMBL:AAW52892.1, ECO:0000313|Proteomes:UP000000531}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35984 / RP62A {ECO:0000313|Proteomes:UP000000531};
RX PubMed=15774886; DOI=10.1128/JB.187.7.2426-2438.2005;
RA Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., Deboy R.T., Ravel J.,
RA Paulsen I.T., Kolonay J.F., Brinkac L., Beanan M., Dodson R.J.,
RA Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA Vamathevan J., Khouri H., Utterback T., Lee C., Dimitrov G., Jiang L.,
RA Qin H., Weidman J., Tran K., Kang K., Hance I.R., Nelson K.E., Fraser C.M.;
RT "Insights on evolution of virulence and resistance from the complete genome
RT analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT strain.";
RL J. Bacteriol. 187:2426-2438(2005).
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DR EMBL; CP000029; AAW52892.1; -; Genomic_DNA.
DR RefSeq; WP_002484438.1; NC_002976.3.
DR AlphaFoldDB; Q5HLD5; -.
DR STRING; 176279.SERP2052; -.
DR REBASE; 28090; SepRPORF2052P.
DR KEGG; ser:SERP2052; -.
DR eggNOG; COG1061; Bacteria.
DR eggNOG; COG3886; Bacteria.
DR HOGENOM; CLU_005588_1_0_9; -.
DR Proteomes; UP000000531; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd09204; PLDc_N_DEXD_b2; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR021835; DUF3427.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025202; PLD-like_dom.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF11907; DUF3427; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:AAW52892.1};
KW Helicase {ECO:0000313|EMBL:AAW52892.1};
KW Hydrolase {ECO:0000313|EMBL:AAW52892.1};
KW Nucleotide-binding {ECO:0000313|EMBL:AAW52892.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000531}.
FT DOMAIN 236..389
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 440..623
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 952 AA; 110545 MW; FB445D73EE021DDD CRC64;
MSNLIQDIKQ SLYKGFIDKD SSHKGNFVPR LLVNNKEENV LSTIIDQLHN CQSFCISVAF
ITESGLASLK SHFYDLSKKG VKGRIITSNY LGFNSPKMFE ELLKLENVEV KLTNIEGFHA
KGYIFEHHNH TSFIIGSSNL TSNALKLNYE HNLFLSTHKN GDLVNNIKYK FDELWDSSFS
LTNEWINEYK QSFEYQTLQK VFDNTVVQNS DIKKFNESKL IKPNLMQEHA LKSLESLRNV
GEEKGLIISA TGTGKTILCA LDVRAYSPDK FLFIVHNEGI LNRAIEEFKK VFPYEDESNF
GLLTGKRKDH DAKFLFATIQ TLSKKENYKL FNSNHFDYIV FDEAHRIAAS SYQKIFNYFK
PNFLLGMTAT PERTDELNIF ELFNYNIAYE IRLQEALESN ILCPFHYFGV TDYIQNEMSQ
EDAFNLKYLA SNERVEHIIK KTNYYGYSGD VLKGLIFVSS RGEAYQLANQ LSKRGISSVG
LTGKDSIAYR AETIQQLKEG SINYIITVDL FNEGIDIPEI NQVVMLRPTK SSIIFIQQLG
RGLRKSTNKE FVTVIDFIGN YKTNYMIPIA LSGNKSQNKD NYRKFLTDTT VLNGVSTINF
EEVAKNKIYN SLDSVKLNQP KLIKEAFNNV KDRIGKLPLL MDFINNDSID PSVIFSRFKN
YYEFLIKNKI IENELSINEF KNLTFLSRQL TPGLKKVDID VLKEIIQNDV TYENLTKKML
NINNDISEYD INTSLSILDF TFFKKTIGKT YGLPLIQYKD NLICLANEFK EALNKPLFNT
FIHDLIDLAN YNNDRYQNKK NSLILYNKYS REDFVKLLNW DKDESGTING YRMKHRTLPL
FITYDKHENI SDNTKYDDEF LSQDELKWYT RSNRKLTSPE VQNILKHEES NTDMYIFVKK
RDDEGKYFYY LGKAKYIKGT EKQDYMPNGN SVVTMHLSMN TSIRDDIYRY IT
//
