ID Q5IS19_9HYPO Unreviewed; 261 AA.
AC Q5IS19;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
DE Flags: Fragment;
GN Name=ech42 {ECO:0000313|EMBL:AAV98509.1};
OS Trichoderma cf. viride D.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=304637 {ECO:0000313|EMBL:AAV98509.1};
RN [1] {ECO:0000313|EMBL:AAV98509.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CPK998 {ECO:0000313|EMBL:AAV98509.1};
RA Druzhinina I.S., Chaverri P., Fallah P., Kubicek C.P., Samuels G.J.;
RT "Hypocrea flavoconidia, a new species with yellow conidia from Costa
RT Rica.";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class V subfamily. {ECO:0000256|ARBA:ARBA00008682}.
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DR EMBL; AY665693; AAV98508.1; -; Genomic_DNA.
DR EMBL; AY665694; AAV98509.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5IS19; -.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1..255
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAV98509.1"
FT NON_TER 261
FT /evidence="ECO:0000313|EMBL:AAV98509.1"
SQ SEQUENCE 261 AA; 28423 MW; 76EDEE14FFE721EF CRC64;
RKNFAKTAIT FMKDWGFDGI DVDWEYPADD TQATNMVLLL KEIRSQLDAY AAQYAPGYHF
LLSIAAPAGP EHYSFLHMSD LGQVLDYVNL MAYDYAGSWS SYSGHDANLF ANPSNSNSSP
YNTDQAIKDY IKGGVPASKI VLGMPIYGRS FESTGGIGQT YSGIGSGSWE NGIWDYKVLP
KAGATVQYDS TAQAYYSYDP SSKELISFDT PAMINTKVSY LKNLGLGGSM FWEASADKTG
SDSLIGTSHR ALGSLDSTQN L
//
