ID Q5IXL1_MONPV Unreviewed; 564 AA.
AC Q5IXL1;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Ankyrin-like protein {ECO:0000313|EMBL:AAY97571.1};
DE SubName: Full=MPXV-COP-158 {ECO:0000313|EMBL:AAX09259.1};
DE SubName: Full=MPXV-SL-158 {ECO:0000313|EMBL:AAW67916.1};
DE SubName: Full=MPXV-WRAIR158 {ECO:0000313|EMBL:AAU01368.1};
GN ORFNames=MPXV-COP-158 {ECO:0000313|EMBL:AAX09259.1}, MPXV-PCH-159
GN {ECO:0000313|EMBL:AIE40955.1}, MPXV-SL-158
GN {ECO:0000313|EMBL:AAW67916.1}, MPXV-UTC-153
GN {ECO:0000313|EMBL:AIE40601.1}, MPXV-WRAIR158
GN {ECO:0000313|EMBL:AAU01368.1}, MPXV_LIB1970_184_179
GN {ECO:0000313|EMBL:AAY97571.1};
OS Monkeypox virus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=10244 {ECO:0000313|EMBL:AAU01368.1, ECO:0000313|Proteomes:UP000172985};
OH NCBI_TaxID=45479; Cynomys gunnisoni (Gunnison's prairie dog) (Spermophilus gunnisoni).
OH NCBI_TaxID=99825; Cynomys leucurus (White-tailed prairie dog).
OH NCBI_TaxID=45480; Cynomys ludovicianus (Black-tailed prairie dog).
OH NCBI_TaxID=99826; Cynomys mexicanus (Mexican prairie dog).
OH NCBI_TaxID=99827; Cynomys parvidens (Utah prairie dog).
OH NCBI_TaxID=30650; Gliridae (dormice).
OH NCBI_TaxID=226685; Heliosciurus ruwenzorii (Ruwenzori sun squirrel).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=10090; Mus musculus (Mouse).
RN [1] {ECO:0000313|EMBL:AAY97571.1, ECO:0000313|Proteomes:UP000127566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liberia_1970_184 {ECO:0000313|EMBL:AAY97571.1};
RX PubMed=16186219; DOI=10.1099/vir.0.81215-0;
RA Likos A.M., Sammons S.A., Olson V.A., Frace A.M., Li Y.,
RA Olsen-Rasmussen M., Davidson W., Galloway R., Khristova M.L.,
RA Reynolds M.G., Zhao H., Carroll D.S., Curns A., Formenty P., Esposito J.J.,
RA Regnery R.L., Damon I.K.;
RT "A tale of two clades: monkeypox viruses.";
RL J. Gen. Virol. 86:2661-2672(2005).
RN [2] {ECO:0000313|Proteomes:UP000143949, ECO:0000313|Proteomes:UP000149280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COP-58 {ECO:0000313|EMBL:AAX09259.1}, MPXV-WRAIR7-61
RC {ECO:0000313|EMBL:AAU01368.1}, and Sierra Leone
RC {ECO:0000313|EMBL:AAW67916.1};
RX PubMed=16023693; DOI=10.1016/j.virol.2005.05.030;
RA Chen N., Li G., Liszewski M.K., Atkinson J.P., Jahrling P.B., Feng Z.,
RA Schriewer J., Buck C., Wang C., Lefkowitz E.J., Esposito J.J., Harms T.,
RA Damon I.K., Roper R.L., Upton C., Buller R.M.;
RT "Virulence differences between monkeypox virus isolates from West Africa
RT and the Congo basin.";
RL Virology 340:46-63(2005).
RN [3] {ECO:0000313|Proteomes:UP000104730, ECO:0000313|Proteomes:UP000117086}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCH {ECO:0000313|EMBL:AIE40955.1}, and UTC
RC {ECO:0000313|EMBL:AIE40601.1};
RX PubMed=25912718; DOI=10.3390/v7042168;
RA Nakazawa Y., Mauldin M.R., Emerson G.L., Reynolds M.G., Lash R.R., Gao J.,
RA Zhao H., Li Y., Muyembe J.J., Kingebeni P.M., Wemakoy O., Malekani J.,
RA Karem K.L., Damon I.K., Carroll D.S.;
RT "A phylogeographic investigation of african monkeypox.";
RL Viruses 7:2168-2184(2015).
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DR EMBL; AY603973; AAU01368.1; -; Genomic_DNA.
DR EMBL; AY741551; AAW67916.1; -; Genomic_DNA.
DR EMBL; AY753185; AAX09259.1; -; Genomic_DNA.
DR EMBL; DQ011156; AAY97571.1; -; Genomic_DNA.
DR EMBL; KJ642614; AIE40601.1; -; Genomic_DNA.
DR EMBL; KJ642616; AIE40955.1; -; Genomic_DNA.
DR SMR; Q5IXL1; -.
DR Proteomes; UP000104730; Genome.
DR Proteomes; UP000117086; Genome.
DR Proteomes; UP000127566; Genome.
DR Proteomes; UP000143949; Genome.
DR Proteomes; UP000149280; Genome.
DR Proteomes; UP000172985; Genome.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR018272; PRANC_domain.
DR PANTHER; PTHR24118:SF99; CHARON; 1.
DR PANTHER; PTHR24118; POTE ANKYRIN DOMAIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF09372; PRANC; 1.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT REPEAT 249..281
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 471..561
FT /note="PRANC"
FT /evidence="ECO:0000259|Pfam:PF09372"
SQ SEQUENCE 564 AA; 66070 MW; A3746AABE439D868 CRC64;
MDFFKKEILD WSIYLFLHYI TRLCSNSSNS SNSSTSHIIQ EYNLVRKYEK VDKTIVDFLS
RWPNLFHILE YGENILHIYF IDAANTNIMI FFLDRVLNIN KNRGSFIHNL GLSSINIKEY
VYQLVNNDHL DNSIRLMLEN GRRTRHFLSY ILDTVNIYIS ILINHRFYID AEDSYGCTLL
HRCIYNYKKS ESESYNELIK ILLNNGSDVD KKDTYGNTPF ILLCKHDIDN AELFEICLEN
ANIDSVDFNG YTPLHYVSCR NKYDFVKLLI SKGANVNARN RFGTTPFYCG IIHGISLIKL
YLESDTELEI DNEHIVRHLI IFDAVESLDY LLSRGVIDIN YRTIYNETSI YDAVSYNAYN
TLVYLLNRNG DFETITTSGC TCISEAVANN NKIIMDILLS KRPSLKIMIP SMIAITKHKQ
HNADLLKMCI KYTACMTDYD TLIDVQSLHQ YKWYILKCFD EIDIMKRCYI KNKTVFQLVF
CIKDINTLMR YGRHPSFVKC NILDVYGSRV RNIIASIRYR QRLISLLSKK LDAGDKWSCF
PNEIKYKILE NFNDNELTTY LKIL
//
